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Dual Inhibitors of Thymidylate Synthase and Dihydrofolate Reductase as Antitumor Agents: Design, Synthesis, and Biological Evaluation of Classical and Nonclassical Pyrrolo2, 3-dpyrimidine Antifolates

机译：胸苷合酶和二氢酚酸还原酶的双抑制剂作为抗肿瘤剂：古典和非生物吡咯的设计，合成和生物学评价2,3-D嘧啶防雾

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1. Dual Inhibitors of Thymidylate Synthase and Dihydrofolate Reductase as Antitumor Agents:Design,Synthesis,and Biological Evaluation of Classical and Nonclassical Pyrrolo[2,3-d]pyrimidine Antifolates~1 [J] . Aleem Gangjee, Hiteshkumar D.Jain, Xin Lin, Journal of Medicinal Chemistry . 2006,第3期

机译：胸苷酸合酶和二氢叶酸还原酶的双重抑制剂作为抗肿瘤药物：经典和非经典吡咯并[2,3-d]嘧啶类抗叶酸剂的设计，合成和生物学评价〜1
2. Design, synthesis, and biological evaluation of classical and nonclassical 2-amino-4-oxo-5-substituted-6-methylpyrrolo[3,2-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors [J] . Gangjee A, Li W, Yang J, Journal of Medicinal Chemistry . 2008,第1期

机译：设计，合成和生物学评估经典和非经典的2-氨基-4-氧代-5-取代的6-甲基吡咯并[3,2-d]嘧啶作为双胸苷酸合酶和二氢叶酸还原酶抑制剂
3. 2,4-Diamino-5-methyl-6-substituted arylthio-furo(2,3-d)pyrimidines as novel classical and nonclassical antifolates as potential dual thymidylate synthase and dihydrofolate reductase inhibitors. [J] . Gangjee A, Jain HD, Phan Bioorganic and medicinal chemistry . 2010,第2期

机译：2,4-二氨基-5-甲基-6-取代的芳硫基-呋喃（2,3-d）嘧啶类化合物是新型的经典和非经典抗叶酸药，它们是潜在的双重胸苷酸合酶和二氢叶酸还原酶抑制剂。
4. Design, Synthesis and Biological Evaluation of the Novel Antitumor Agent 2H-benzob1, 4oxazin-3(4H)-one and Its Derivatives [C] . Huanhuan Li, Kailin Han, Qiannan Guo, International symposium on IT in medicine and education . 2014

机译：新型抗肿瘤药2H-苯并b 1,4恶嗪-3（4H）-one及其衍生物的设计，合成及生物学评价
5. The synthesis of monocyclic and bicyclic inhibitors of dihydrofolate reductase and thymidylate synthase. [D] . Kothare, Mohit. 1998

机译：二氢叶酸还原酶和胸苷酸合酶的单环和双环抑制剂的合成。
6. Dual Inhibitors of Thymidylate Synthase and Dihydrofolate Reductase as Antitumour Agents: Design Synthesis and Biological Evaluation of Classical and Nonclassical Pyrrolo23-dpyrimidine Antifolates [O] . Aleem Gangjee, Hiteshkumar D. Jain, Jaclyn Phan, -1

机译：胸苷酸合酶和二氢叶酸还原酶的双重抑制剂作为抗肿瘤药：经典和非经典吡咯并23-d嘧啶类抗叶酸药物的设计合成和生物学评价
7. Design, Synthesis, and X-ray Crystal Structure of Classical and Nonclassical 2-Amino-4-oxo-5-substituted-6-ethylthieno2,3-dpyrimidines as Dual Thymidylate Synthase and Dihydrofolate Reductase Inhibitors and as Potential Antitumor Agents [O] . Aleem Gangjee, Wei Li, Roy L. Kisliuk, 2009

机译：经典和非生物学2-氨基-4-氧代-5-取代-6-乙基硫胺2,3-D嘧啶的设计，合成和X射线晶体结构作为双胸苷合酶和二氢醇还原酶抑制剂和潜在的抗肿瘤剂

Dual Inhibitors of Thymidylate Synthase and Dihydrofolate Reductase as Antitumor Agents: Design, Synthesis, and Biological Evaluation of Classical and Nonclassical Pyrrolo2, 3-dpyrimidine Antifolates

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