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Complete Disruption of Autism-Susceptibility Genes by Gene-Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons

机译：通过基因编辑完全破坏自闭症易感性基因，主要是降低了中源性人神经元的功能性连通性

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Eric Deneault; Sean H. White; Deivid C. Rodrigues; P. Joel Ross; Muhammad Faheem; Kirill Zaslavsky; Zhuozhi Wang; Roumiana Alexandrova; Giovanna Pellecchia; Wei Wei; Alina Piekna; Gaganjot Kaur; Jennifer L. Howe; Vickie Kwan; Bhooma Thiruvahindrapuram; Susan Walker; Peter Pasceri; Daniele Merico; Ryan K.C. Yuen; Karun K. Singh; James Ellis; Stephen W. Scherer;
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1. Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons [J] . Eric Deneault, Sean H. White, Deivid C. Rodrigues, Stem Cell Reports . 2018,第5期

机译：通过基因编辑完全破坏自闭症易感性基因主要减少等基因人类神经元的功能连接。
2. NN eonatal mouse cortical but not isogenic human astrocyte feeder layers enhance the functional maturation of induced pluripotent stem cell‐derived neurons in culture [J] . Lischka Fritz W., Efthymiou Anastasia, Zhou Qiong, Glia . 2018,第4期

机译： n n eonatal小鼠皮质但不是等源人星形胶质细胞饲养层增强培养中诱导多能干细胞衍生神经元的功能成熟
3. Disrupted interhemispheric resting-state functional connectivity and structural connectivity in first-episode, treatment-naive generalized anxiety disorder [J] . Wang Wei, Peng Zhaohui, Wang Xiang, Journal of affective disorders . 2019,第期

机译：在一集，治疗 - 幼稚广泛性焦虑症中扰乱了互脱休息状态功能连通性和结构连通性
4. Functional Connectivity between Layer 2/3 and Layer 5 Neurons in Prefrontal Cortex of Nonhuman Primates during a Delayed Match-to-Sample Task [C] . Dong Song, Ioan Opris, Rosa H. M. Chan, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2012

机译：在延迟匹配 - 样本任务期间，在延迟匹配匹配任务期间，第2/3层和第5层和第5层神经元之间的功能连通性
5. Modeling SCN1A Epilepsy with Dual Isogenic Pairs of Human iPSC-derived Neurons [D] . Xie, Yunyao. 2019

机译：用双胞胎源性对人IPSC衍生的神经元进行建模SCN1A癫痫
6. Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons [O] . Eric Deneault, Sean H. White, Deivid C. Rodrigues, 2019

机译：通过基因编辑完全破坏自闭症易感性基因主要减少了等基因人类神经元的功能连接。
7. Faculty Opinions recommendation of Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons. [O] . Christine Mummery 2018

机译：通过基因编辑，教师提出完全破坏自闭症易感性基因的建议，主要是降低了等源性人神经元的功能性连通性。

Complete Disruption of Autism-Susceptibility Genes by Gene-Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons

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