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Advantage of a Co-expression System for Estimating Physiological Effects of Functional Interaction Between Cytochrome P450 3A4 and Uridine 5’-Diphospho-Glucuronosyltransferase 2B7

机译：一种共表达系统，用于估计细胞色素P450 3A4与尿苷5'-二磷葡萄糖糖基三转移酶2B7的功能相互作用的生理效应

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Yuu Miyauchi; Hideyuki Yamada; Yuji Ishii;
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1. Physiologically-based pharmacokinetic modeling for mirabegron: a multi-elimination pathway mediated by cytochrome P450 3A4, uridine 5'-diphosphate-glucuronosyltransferase 2B7, and butyrylcholinesterase [J] . Konishi Kentaro, Minematsu Tsuyoshi, Nagasaka Yasuhisa, Xenobiotica: the fate of foreign compounds in biological systems . 2019,第7a12期

机译：Mirabegron基于生理学药代动力学建模：由细胞色素P450 3A4，尿苷5'-二磷酸 - 葡糖醛糖基转移酶2B7和丁二醇预防酶介导的多消除途径
2. Effects of co-treatment with sulforaphane and autophagy modulators on uridine 5 '-diphospho-glucuronosyltransferase 1A isoforms and cytochrome P450 3A4 expression in Caco-2 human colon cancer cells [J] . Wang Min, Zhu Jing-Yu, Chen Shuo, Oncology letters . 2014,第6期

机译：萝卜硫烷和自噬调节剂共同处理对人结肠癌Caco-2细胞尿苷5'-二磷酸-葡萄糖醛糖基转移酶1A亚型和细胞色素P450 3A4表达的影响
3. Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: Effects of cytochrome P450-P450 and cytochrome P450-b(5) interactions [J] . Yamazaki H, Gillam EMJ, Dong MS, Archives of Biochemistry and Biophysics . 1997,第2期

机译：重组重组细胞色素P450 2C10（2C9）并与细胞色素P450 3A4和其他形式进行比较：细胞色素P450-P450和细胞色素P450-b（5）相互作用的影响
4. Functionalization of cytochrome p450cam monooxygenase system utilizing water-in-oil(W/O)emulsions [C] . China-Japan-Korea Joint Symposium on Enzyme Engineering . 2004

机译：利用油包水（W / O）乳液功能化细胞色素p450cam单加氧酶系统
5. In vitro interactions of natural health products with P-glycoprotein (P-gp) and cytochrome P450 3A4 (CYP3A4): Relevance to HIV therapies (Immune deficiency). [D] . Budzinski, Jason William. 2003

机译：天然保健品与P-糖蛋白（P-gp）和细胞色素P450 3A4（CYP3A4）的体外相互作用：与HIV治疗的相关性（免疫缺陷）。
6. Effects of co-treatment with sulforaphane and autophagy modulators on uridine 5′-diphospho-glucuronosyltransferase 1A isoforms and cytochrome P450 3A4 expression in Caco-2 human colon cancer cells [O] . MIN WANG, JING-YU ZHU, SHUO CHEN, -1

机译：萝卜硫烷和自噬调节剂共同处理对人结肠癌Caco-2细胞尿苷5-二磷酸-葡萄糖醛糖基转移酶1A亚型和细胞色素P450 3A4表达的影响
7. Interaction of Cytochrome P450 3A4 and UDP-Glucuronosyltransferase 2B7: Evidence for Protein-Protein Association and Possible Involvement of CYP3A4 J-Helix in the Interaction [O] . Takeda Shuso, Ishii Yuji, Iwanaga Megumi, 2009

机译：细胞色素P450 3A4和UDP-葡萄糖醛酸转移酶2B7的相互作用：蛋白质-蛋白质结合的证据和CYP3A4 J-螺旋在相互作用中的可能参与

Advantage of a Co-expression System for Estimating Physiological Effects of Functional Interaction Between Cytochrome P450 3A4 and Uridine 5’-Diphospho-Glucuronosyltransferase 2B7

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