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GC1118, an Anti-EGFR Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity against High-Affinity EGFR Ligands

机译：GC1118，一种抗EGFR抗体，具有明显的结合表位和对高亲和力EGFR配体的优异抑制活性

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Yangmi Lim; Jiho Yoo; Min-Soo Kim; Minkyu Hur; Eun Hee Lee; Hyung-Suk Hur; Jae-Chul Lee; Shi-Nai Lee; Tae Wook Park; Kyuhyun Lee; Ki Hwan Chang; Kuglae Kim; YingJin Kang; Kwang-Won Hong; Se-Ho Kim; Yeon-Gil Kim; Yeup Yoon; Do-Hyun Nam; Heekyoung Yang; Dong Geon Kim; Hyun-Soo Cho; Jonghwa Won;
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1. GC1118, an Anti-EGFR Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity against High-Affinity EGFR Ligands [J] . Lim Yangmi, Yoo Jiho, Kim Min-Soo, Molecular cancer therapeutics . 2016,第2期

机译：GC1118，具有独特的结合表位和对高亲和力EGFR配体具有优异抑制活性的抗EGFR抗体
2. GC1118, a novel anti-EGFR antibody, has potent KRAS mutation-independent antitumor activity compared with cetuximab in gastric cancer [J] . Park Ji Eun, Jin Mei Hua, Hur Minkyu, Gastric cancer: official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association . 2019,第5期

机译：GC1118是一种新型的抗EGFR抗体，与胃癌中的西替昔单抗相比，具有有效的KRAS突变抗肿瘤活性
3. Nimotuzumab: a novel anti-EGFR monoclonal antibody that retains anti-EGFR activity while minimizing skin toxicity. [J] . Boland WK, Bebb G Expert opinion on biological therapy . 2009,第9期

机译：Nimotuzumab：一种新型抗EGFR单克隆抗体，在保留抗EGFR活性的同时将皮肤毒性降至最低。
4. High-affinity FGFR2 Binding Peptides Derived from the Native Epitope of the KGF Ligand [C] . Yijun Pan, Yvonne M. Angell, Jennifer M. Green American Peptide Symposium . 2009

机译：高亲和力FGFR2衍生自KGF配体的天然表位的结合肽
5. Structural studies of an inhibitory antibody, Mab41.4, to its epitope, ATF-1. [D] . Mazlo, Johanna. 2001

机译：针对其表位ATF-1的抑制性抗体Mab41.4的结构研究。
6. Promising Therapeutic Efficacy of GC1118 an Anti-EGFR Antibody against KRAS Mutation-Driven Colorectal Cancer Patient-Derived Xenografts [O] . Hye Won Lee, Eunju Son, Kyoungmin Lee, 2019

机译：抗EGFR抗体GC1118对KRAS突变驱动的结直肠癌患者衍生的异种移植物的有希望的治疗功效
7. Anti-EGFR Monoclonal Antibody GC1118 [O] . 2020

机译：抗EGFR单克隆抗体GC1118

GC1118, an Anti-EGFR Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity against High-Affinity EGFR Ligands

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