Results of integrated treatment of herpetic stomatitis with the inclusion of lipid concentrate of ERYX biomass

摘要

Aim. The study of the effectiveness of the use of the biologically active additive Reptin-plant in the complex treatment of patients with herpetic stomatitis.Materials and methods. We examined 189 patients with a diagnosis of herpetic stomatitis, which were divided into 2 groups depending on the receipt of complex antiviral therapy with the inclusion of ERYX biomass lipid concentrate in the treatment regimen and without it. The following were assessed: clinical status, index assessment of the state of the oral cavity, state of local immunity, frequency of relapses and duration of the latency period.Results. 57 (30.2%) patients were identified with a mild form of herpetic stomatitis (HS), the average severity of HS was determined in 93 (49.2%) and a severe course of the disease was diagnosed in 39 (20.6%) patients. Analysis of the index assessment of the state of the oral cavity (OHIS, PMA), molecular genetic parameters, immunological studies (lysozyme titer, phagocytosis, concentration of sIg A in saliva) showed a statistically significant difference when included in the complex treatment of Reptin-plant, demonstrating the benefits of using it.Conclusions. The use of ERYX biomass lipid concentrate in the complex treatment of herpetic stomatitis effectively affects the dynamics of the course of the disease, improves the quality of life of patients.