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Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp13 Helicase

机译：通过筛选NSP13螺旋酶的小分子抑制剂来识别SARS-COV-2抗病毒化合物

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Jingkun Zeng; Florian Weissmann; Agustina P. Bertolin; Viktor Posse; Berta Canal; Rachel Ulferts; Mary Wu; Ruth Harvey; Saira Hussain; Jennifer C. Milligan; Chloe Roustan; Annabel Borg; Laura McCoy; Lucy S. Drury; Svend Kjaer; John McCauley; Michael Howell; Rupert Beale; John F.X Diffley;
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1. In silico screening of small molecule libraries using the dengue virus envelope E protein has identified compounds with antiviral activity against multiple flaviviruses. [J] . Kampmann T, Yennamalli R, Campbell Antiviral Research . 2009,第3期

机译：在使用登革热病毒包膜E蛋白的小分子文库的计算机筛选中，已鉴定出对多种黄病毒具有抗病毒活性的化合物。
2. Genomic-based high throughput screening identifies small molecules that differentially inhibit the antiviral and immunomodulatory effects of IFN-alpha. [J] . Chen B, Zong Q, Cibotti R, Molecular medicine. . 2008,第7a8期

机译：基于基因组的高通量筛选可识别出差异抑制IFN-α的抗病毒和免疫调节作用的小分子。
3. A computational approach for the screening of potential antiviral compounds against SARS-CoV-2 protease: Ionic liquid vs herbal and natural compounds [J] . Saraswat Juhi, Singh Prashant, Patel Rajan Journal of Molecular Liquids . 2021,第1期

机译：对SARS-COV-2蛋白酶的潜在抗病毒化合物筛选的计算方法：离子液体与草药和天然化合物
4. Deep learning-assisted pipeline for Virtual Screening of ligand compound databases: Application on inhibiting the entry of SARS-CoV-2 into human cells [C] . Stelios Mylonas, Apostolos Axenopoulos, Sotiris Katsamakas, IEEE International Conference on Bioinformatics and Bioengineering . 2020

机译：用于配体化合物数据库的深筛选深层学习辅助管道：抑制SARS-COV-2进入人细胞的应用
5. Unfolded protein response inhibitors identified by high throughput screening of a combinatorial chemistry compound library [D] . Martel-Lorion, Chloe 2004

机译：通过高通量筛选组合化学化合物库鉴定出未折叠的蛋白质反应抑制剂
6. Genomic-Based High Throughput Screening Identifies Small Molecules That Differentially Inhibit the Antiviral and Immunomodulatory Effects of IFN-α [O] . Bo Chen, Qin Zong, Ricardo Cibotti, 2008

机译：基于基因组的高通量筛选可识别差异性抑制IFN-α的抗病毒和免疫调节作用的小分子。
7. Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp3 Papain-like Protease [O] . Chew Theng Lim, Kang Wei Tan, Mary Wu, 2021

机译：通过筛选NSP3木瓜蛋白酶的小分子抑制剂来识别SARS-COV-2抗病毒化合物

Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp13 Helicase

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