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PI3K/mTOR Dual Inhibitor PF-04691502 Is a Schedule-Dependent Radiosensitizer for Gastroenteropancreatic Neuroendocrine Tumors

机译：PI3K / mTOR双抑制剂PF-04691502是一种依赖胃肠内科神经内分泌肿瘤的依赖性辐射敏化剂

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Zeta Chow; Jeremy Johnson; Aman Chauhan; Tadahide Izumi; Michael Cavnar; Heidi Weiss; Courtney M. Townsend; Lowell Anthony; Carrigan Wasilchenko; Matthew L. Melton; Jörg Schrader; B. Mark Evers; Piotr Rychahou;
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1. Antitumor activity of the dual PI3K/MTOR inhibitor, PF-04691502, in combination with radiation in head and neck cancer [J] . Tonlaar Nathan, Galoforo Sandra, Thibodeau Bryan J., Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2017,第3期

机译：双PI3K / mTOR抑制剂，PF-04691502的抗肿瘤活性，与头部和颈部癌症的辐射相结合
2. Dual Inhibition of PI3K and mTORC1/C2 by PKI-587 (PF-05212384) as a Promising Therapeutic Option for Gastroenteropancreatic Neuroendocrine Tumor Disease and Its Effect on AKT-Signaling [J] . Freitag H., Briest F., Christen F., Neuroendocrinology: International Journal for Basic and Clinical Studies on Neuroendocrine Relationships . 2015,第1a2期

机译：PKI-587（PF-05212384）对PI3K和mTORC1 / C2的双重抑制作为胃肠道胰腺神经内分泌肿瘤疾病的有前途的治疗选择及其对AKT信号的影响
3. PI3K/mTOR inhibitor PF-04691502 antitumor activity is enhanced with induction of wild-type TP53 in human xenograft and murine knockout models of head and neck cancer [J] . HerzogA., BianY., BroekR.V., Clinical cancer research: an official journal of the American Association for Cancer Research . 2013,第14期

机译：PI3K / mTOR抑制剂PF-04691502诱导人头颈癌异种移植和小鼠基因敲除模型中的野生型TP53可增强抗肿瘤活性
4. Combination of PI3K/Akt/mTOR inhibitors and PDT in endothelial and tumor cells. [C] . Fateye, Babasola, Chen Bin Optical methods for tumor treatment and detection: mechanisms and techniques in photodynamic therapy XX . 2011

机译：内皮细胞和肿瘤细胞中PI3K / Akt / mTOR抑制剂和PDT的组合。
5. Improving Survival Prognostication of Gastroenteropancreatic Neuroendocrine Tumors [D] . Martin, Jacob A. 2017

机译：改善胃肠道胰腺神经内分泌肿瘤的生存预后
6. Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a PIK3CA Mutation [O] . Douglas D. Fang, Cathy C. Zhang, Yin Gu, -1

机译：PI3K / mTOR双重抑制剂PF-04691502在具有PIK3CA突变的结直肠癌干细胞衍生的人异种移植肿瘤模型中的抗肿瘤功效。
7. Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a PIK3CA Mutation. [O] . Douglas D Fang, Cathy C Zhang, Yin Gu, 2013

机译：双pI3K / mTOR抑制剂pF-04691502在来源于携带pIK3Ca突变的结肠直肠癌干细胞的人异种移植肿瘤模型中的抗肿瘤效力。

PI3K/mTOR Dual Inhibitor PF-04691502 Is a Schedule-Dependent Radiosensitizer for Gastroenteropancreatic Neuroendocrine Tumors

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