首页> 外文OA文献 >Drug Repurposing for Coronavirus (COVID-19): In Silico Screening of Known Drugs Against the SARS-CoV-2 Spike Protein Bound to Angiotensin Converting Enzyme 2 (ACE2) (6M0J)

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Drug Repurposing for Coronavirus (COVID-19): In Silico Screening of Known Drugs Against the SARS-CoV-2 Spike Protein Bound to Angiotensin Converting Enzyme 2 (ACE2) (6M0J)

机译：冠状病毒（Covid-19）的药物重新促使：在与血管紧张素转化酶2（ACE2）结合的SARS-COV-2穗蛋白的SARS-COV-2穗蛋白的硅筛选（6M0J）中

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Konstantinos Kalamatianos;
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1. Repurposing FDA-approved drugs to fight COVID-19 using in silico methods: Targeting SARS-CoV-2 RdRp enzyme and host cell receptors (ACE2, CD147) through virtual screening and molecular dynamic simulations [J] . Soodeh Mahdian, Mahboobeh Zarrabi, Yunes Panahi, Informatics in Medicine Unlocked . 2021,第a期

机译：通过在硅中释放FDA批准的药物来对抗Covid-19，在Silico 方法：通过虚拟筛选和分子动态模拟靶向SARS-COV-2 RDRP酶和宿主细胞受体（ACE2，CD147）
2. Testing of natural products in clinical trials targeting the SARS-CoV-2 (Covid-19) viral spike protein-angiotensin converting enzyme-2 (ACE2) interaction [J] . Biochemical Pharmacology . 2020,第期

机译：临床试验中的天然产物测试靶向SARS-COV-2（Covid-19）病毒穗蛋白 - 血管紧张素转换酶-2（ACE2）相互作用
3. Leaving no stone unturned: Allosteric targeting of SARS-CoV-2 spike protein at putative druggable sites disrupts human angiotensin-converting enzyme interactions at the receptor binding domain [J] . Fisayo A. Olotu, Kehinde F. Omolabi, Mahmoud E.S. Soliman Informatics in Medicine Unlocked . 2020,第a期

机译：留下没有石头的：在推定的毒毒率下SARS-COV-2尖峰蛋白的变构靶向破坏了受体结合结构域的人血管紧张素转换酶相互作用
4. The Prevalence of Potential Clinically Significant Drug Interactions with Angiotensin-Converting Enzyme Inhibitors in Slovenia [C] . Marjetka P., Brane L, Polonca F. European Congress of Pharmacology . 2012

机译：斯洛文尼亚血管紧张素转化酶抑制剂潜在临床显着的药物相互作用的患病率
5. Modulation of angiotensin-converting enzyme 2 (ACE2) expression, subcellular localization, and enzymatic activity by angiotensin II: Implication in neurogenic hypertension. [D] . Deshotels, Matthew R. 2013

机译：血管紧张素II对血管紧张素转化酶2（ACE2）表达，亚细胞定位和酶活性的调节：在神经性高血压中的意义。
6. Target-Centered Drug Repurposing Predictions of Human Angiotensin-Converting Enzyme 2 (ACE2) and Transmembrane Protease Serine Subtype 2 (TMPRSS2) Interacting Approved Drugs for Coronavirus Disease 2019 (COVID-19) Treatment through a Drug-Target Interaction Deep Learning Model [O] . Yoonjung Choi, Bonggun Shin, Keunsoo Kang, 2020

机译：人血管紧张素转化酶2（ACE2）和跨膜蛋白酶丝氨酸亚型2（TMPRSS2）的靶向药物修复预测通过药物 - 靶互动深层学习模型进行冠状病毒疾病的批准药物（Covid-19）治疗
7. Testing of natural products in clinical trials targeting the SARS-CoV-2 (Covid-19) viral spike protein-angiotensin converting enzyme-2 (ACE2) interaction [O] . Gary Williamson, Asimina Kerimi 2020

机译：临床试验中的天然产物测试靶向SARS-COV-2（Covid-19）病毒穗蛋白 - 血管紧张素转换酶-2（ACE2）相互作用

Drug Repurposing for Coronavirus (COVID-19): In Silico Screening of Known Drugs Against the SARS-CoV-2 Spike Protein Bound to Angiotensin Converting Enzyme 2 (ACE2) (6M0J)

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