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Complete responses in patients with second-line or greater metastatic triple negative breast cancer (TNBC) following first-in-human immunotherapy combining NK and T cell activation with off-the-shelf high-affinity CD16 NK cell line (haNK)

机译：在将NK和T细胞活化与离上的高亲和力CD16 NK细胞系（HANK）结合NK和T细胞活化之后，在二线或更大的转移性三重阴性乳腺癌（TNBC）患者中完全反应。

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C. Nangia; P. Soon-Shiong; S. Rabizadeh; J.H. Lee; L. Sender; F. Jones; M. Kistler; K. Niazi; T. Seery; A. Rock; O. Jafari;
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1. Safety and efficacy from first-in-human immunotherapy combining NK and T cell activation with off-the-shelf high-affinity CD16 NK cell line (haNK) in patients with 2nd-line or greater metastatic triple-negative breast cancer (TNBC) [J] . Intelligence: A Multidisciplinary Journal . 2020,第期

机译：第一单免疫治疗的安全性和疗效与二线或更高转移性三重阴性乳腺癌（TNBC）的患者中与现成的高亲和力CD16 NK细胞系（HANK）组合的NK和T细胞活化。（TNBC）
2. Phase 1/2 first-in-human study of U3-1402, an anti-human epidermal growth factor receptor 3 (HER3) antibody-drug conjugate, in HER3-expressing advanced/unresectable or metastatic breast cancer, including those with triple negative breast cancer (TNBC) or HER3-low disease [J] . Intelligence: A Multidisciplinary Journal . 2020,第期

机译：阶段1/2 U3-1402的第一人体研究，抗人表皮生长因子受体3（HER3）抗体 - 药物缀合物，在HER3表达先进/不可切除或转移性乳腺癌中，包括三重阴性乳房癌症（TNBC）或HER3低疾病
3. N-Linked glycosylation profiles of therapeutic induced senescent (TIS) triple negative breast cancer cells (TNBC) and their extracellular vesicle (EV) progeny [J] . Emma L. Kavanagh, Melinda Halasz, Paul Dowling, Molecular BioSystems . 2021,第1期

机译：治疗诱导的衰老（TIS）三重阴性乳腺癌细胞（TNBC）及其细胞外囊泡（EV）后代的N-连接糖基化谱
4. TNF siRNA as Modulators of Apoptosis and Angiogenesis, in Cell Migration and Invasion in Triple Negative Breast Cancer Cells (TNBC) [C] . Ioana Berindan Neagoe, Valentina Pileczki, Roxana Cojocneanu Petric, Molecular Medicine TRI-CON. . 2014

机译：TNF siRNA作为细胞凋亡和血管生成的调节剂，在三重阴性乳腺癌细胞中的细胞迁移和侵袭中（TNBC）
5. The Attenuating Effects of 1,2,3,4,6-Penta-O-Galloyl-β-D Glucose (PGG) on the Inflammatory Cytokines Release in TNF-α-activated Triple Negative Breast Cancer (TNBC) Cells [D] . Alghamdi, Sumiah. 2019

机译：1,2,3,4,6-五核苷酸-β-D葡萄糖（PGG）对TNF-α-活化的三阴性乳腺癌（TNBC）细胞炎症细胞因子释放的衰减效应
6. p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer [O] . Emily Powell, Jiansu Shao, Yuan Yuan, 2016

机译：与B细胞易位基因2（BTG2）丢失有关的p53缺乏症通过促进三阴性乳腺癌患者源性异种移植（PDX）模型中原发和转移部位的肿瘤生长来增强转移潜力
7. Effects of Hsp90 Inhibitors on Patient Derived Triple Negative Breast Cancer (TNBC) Cells: BRCA1 as a Therapeutic Target for TNBC [O] . Shrikant Anant, Prabhu Ramamoorthy, Ossama Tawfik, 2017

机译：HSP90抑制剂对患者衍生三重阴性乳腺癌（TNBC）细胞的影响：BRCA1作为TNBC的治疗靶标
8. Strategies to Counteract Resistance Mechanisms in CAR+ T-Cell-Based Immunotherapy for Triple-Negative Breast Cancer. [R] . Ferrone, S. 2017

机译：抵抗基于CaR + T细胞的三阴性乳腺癌免疫治疗耐药机制的策略。

Complete responses in patients with second-line or greater metastatic triple negative breast cancer (TNBC) following first-in-human immunotherapy combining NK and T cell activation with off-the-shelf high-affinity CD16 NK cell line (haNK)

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