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Exploration of 2 + 2 + 2 cyclotrimerisation methodology to prepare tetrahydroisoquinoline-based compounds with potential aldo–keto reductase 1C3 target affinity

机译：探测2 + 2 + 2旋转反式化方法，制备具有潜在Aldo-keto还原酶1C3靶性亲和力的四氢异喹啉基化合物

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Ana R. N. Santos; Helen M. Sheldrake; Ali I. M. Ibrahim; Chhanda Charan Danta; Davide Bonanni; Martina Daga; Simonetta Oliaro-Bosso; Donatella Boschi; Marco L. Lolli; Klaus Pors;
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1. Exploration of [2 + 2 + 2] cyclotrimerisation methodology to prepare tetrahydroisoquinolinebased compounds with potential aldo-keto reductase 1C3 target affinity [J] . Ana R. N. Santos, Helen M. Sheldrake, Ali I. M. Ibrahim, MedChemComm . 2019,第8期

机译：[2 + 2 + 2]旋转反式化方法的探索用潜在的Aldo-Keto还原酶1C3靶性亲和力制备四氢异喹啉基化合物
2. An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone i [J] . Byrns MC, Steckelbroeck S, Penning TM Biochemical Pharmacology . 2008,第2期

机译：吲哚美辛类似物N-（4-氯苯甲酰基）-褪黑激素是醛固酮还原酶1C3（2型3α-HSD，5型17beta-HSD和前列腺素F合酶）的选择性抑制剂。激素依赖和激素我
3. Roscovitine and purvalanol A effectively reverse anthracycline resistance mediated by the activity of aldo-keto reductase 1C3 (AKR1C3): A promising therapeutic target for cancer treatment [J] . Eva Novotná, Neslihan Büküm, Jakub Hofman, Biochemical Pharmacology . 2018,第期

机译：Roscovitine和Purvalanol A有效地逆转蒽环旋转型抗性由Aldo-Keto还原酶1C3（AKR1C3）的活性介导：癌症治疗的有希望的治疗靶标
4. STRUCTURAL AND BIOCHEMICAL STUDIES OF NOVEL ALDO-KETO REDUCTASES (AKRS) FOR THE BIOCATALYTIC CONVERSION OF 3-HYDROXYBUTANAL TO 1,3-BUTANEDIOL [C] . Taeho Kim, Robert Flick, Joseph Brunzelle, Biochemical and molecular engineering XX: the next generation of biochemical engineering: from nanoscale to industrial scale . 2017

机译：新型醛基酮还原酶（AKRS）从3-羟基丁二醛向1,3-丁二酚的生物催化转化的结构和生物化学研究
5. The Role of Aldo-Keto Reductases and Estrogen Signalling in Acquired Anthracycline Resistance [D] . Chewchuk, Simon 2011

机译：醛固酮还原酶和雌激素信号传导在获得性蒽环类抗药性中的作用
6. Exploration of 2 + 2 + 2 cyclotrimerisation methodology to prepare tetrahydroisoquinoline-based compounds with potential aldo–keto reductase 1C3 target affinity [O] . Ana R. N. Santos, Helen M. Sheldrake, Ali I. M. Ibrahim, 2019

机译：探测2 + 2 + 2旋转反式化方法制备具有潜在Aldo-keto还原酶1C3靶性亲和力的四氢异喹啉基化合物
7. An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3α-HSD, type 5 17β-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent malignancies [O] . Michael C. Byrns, Stephan Steckelbroeck, Trevor M. Penning 2008

机译：吲哚汀类似物，N-（4-氯苯甲酰基）-Melatonin是Aldo-keto还原酶1c3（2型3α-HSD，517β-HSD和前列腺素F合酶）的选择性抑制剂，潜在的治疗靶标激素依赖和激素独立恶性肿瘤

Exploration of 2 + 2 + 2 cyclotrimerisation methodology to prepare tetrahydroisoquinoline-based compounds with potential aldo–keto reductase 1C3 target affinity

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