首页> 外文OA文献 >Inactivation of S-Adenosyl-l-homocysteine Hydrolase by 6-Cyano-5, 6-didehydro-6-deoxyhomoadenosine and 6-Chloro-6-cyano-5, 6-didehydro-6-deoxyhomoadenosine. Antiviral and Cytotoxic Effects

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Inactivation of S-Adenosyl-l-homocysteine Hydrolase by 6-Cyano-5, 6-didehydro-6-deoxyhomoadenosine and 6-Chloro-6-cyano-5, 6-didehydro-6-deoxyhomoadenosine. Antiviral and Cytotoxic Effects

机译：将S-腺苷-1-同型半胱氨酸水解酶的灭活6-氰基-5,6-脱邻-6-脱氧核苷酸和6-氯-6-氰基-5,6-二邻-6-脱氧酚酶。抗病毒和细胞毒性效应

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1. Inactivation of S-adenosyl-L-homocysteine hydrolase by 6 '-cyano-5 ',6 '-didehydro-6 '-deoxyhomoadenosine and 6 '-chloro-6 '-cyano-5 ',6 '-didehydro-6 '-deoxyhomoadenosine. Antiviral and cytotoxic effects [J] . Guillerrn G, Muzard M, Glapski C, Journal of Medicinal Chemistry . 2006,第4期

机译：通过6'-cyano-5'，6'-didehydro-6'-deoxyhomoadenosine和6'-chloro-6'-cyano-5'，6'-didehydro-6'-灭活S-腺苷-L-高半胱氨酸水解酶脱氧高腺苷。抗病毒和细胞毒性作用
2. Inactivation of S-Adenosyl-L-Homocysteine hydrolase with novel 5'-thioadenosine derivatives. Antiviral effects. [J] . Guillerm G, Guillerm D, Vandenplas Vitkowski C, Bioorganic and Medicinal Chemistry Letters . 2003,第10期

机译：用新型5'-硫代腺苷衍生物灭活S-腺苷-L-高半胱氨酸水解酶。抗病毒作用。
3. Stereoselective synthesis of sugar-modified enyne analogues of adenosine and uridine. Interaction with S-adenosyl-L-homocysteine hydrolase and antiviral and cytotoxic effects [J] . Wnuk SF, Lewandowska E, Sacasa PR, Journal of Medicinal Chemistry . 2004,第21期

机译：糖修饰的腺苷和尿苷的烯炔类似物的立体选择性合成。与S-腺苷-L-高半胱氨酸水解酶的相互作用以及抗病毒和细胞毒性作用
4. The antiviral drug ribavirin is a selective inhibitor of S-adenosyl-L-homocysteine hydrolase from Trypanosoma cruzi [O] . Sumin Cai, Qing-Shan Li, Ronald T. Borchardt, -1

机译：抗病毒药物利巴韦林是克氏锥虫S-腺苷-L-高半胱氨酸水解酶的选择性抑制剂
5. Inactivation of S-adenosyl-L-homocysteine hydrolase by cAMP results from dissociation of enzyme-bound NAD+. [O] . Hohman, R J, Guitton, M C, Veron, M 1985

机译：cAMP使S-腺苷-L-高半胱氨酸水解酶失活是由于酶结合的NAD +的解离所致。

Inactivation of S-Adenosyl-l-homocysteine Hydrolase by 6-Cyano-5, 6-didehydro-6-deoxyhomoadenosine and 6-Chloro-6-cyano-5, 6-didehydro-6-deoxyhomoadenosine. Antiviral and Cytotoxic Effects

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