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Activation of the PI3K/AKT signalling pathway in non-melanoma skin cancer is not mediated by oncogenic PIK3CA and AKT1 hotspot mutations

机译：在非黑色素瘤皮肤癌中的PI3K / AKT信号传导途径的激活未被致癌PIK3CA和AKT1热点突变介导

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Christian Hafner; Michael Landthaler; Thomas Vogt;
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年度 2010
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1. Activation of the PI3K/AKT signalling pathway in non-melanoma skin cancer is not mediated by oncogenic PIK3CA and AKT1 hotspot mutations. [J] . Hafner C, Landthaler M, Vogt T Experimental dermatology . 2010,第8期

机译：非黑色素瘤皮肤癌中PI3K / AKT信号通路的激活不由致癌性PIK3CA和AKT1热点突变介导。
2. PI3K signaling pathway is activated by PIK3CA mRNA overexpression and copy gain in prostate tumors, but PIK3CA, BRAF, KRAS and AKT1 mutations are infrequent events [J] . Laia Agell, Silvia Hernández, Marta Salido, Modern Pathology . 2011,第3期

机译：PI3K信号通路被前列腺肿瘤中的PIK3CA mRNA过表达和复制增加激活，但PIK3CA，BRAF，KRAS和AKT1突变很少发生
3. 803 PI3K signalling pathway is activated by PIK3CA gain and overexpression in prostate tumours, but PI3KCA, BRAF, KRAS AND AKT1 mutations are an infrequent event [J] . L.Agell, S.Hernandez, S.de Muga, European Journal of Cancer Supplements . 2010,第5期

机译：803 PI3K信号通路被前列腺肿瘤中的PIK3CA增益和过表达激活，但PI3KCA，BRAF，KRAS和AKT1突变很少发生
4. Inspecting the Role of PI3K/AKT Signaling Pathway in Cancer Development Using an In Silico Modeling and Simulation Approach [C] . Pedro Pablo Gonzalez-Perez, Maura Cardenas-Garcia International work-conference on bioinformatics and biomedical engineering . 2018

机译：使用计算机模拟和仿真方法检查PI3K / AKT信号通路在癌症发展中的作用
5. Sensitivity of MCF-7 breast cancer cells to anticancer drugs is decreased by activation of the PI3K/PDK/Akt signal transduction pathway. [D] . Navolanic, Patrick M. 2004

机译：通过激活PI3K / PDK / Akt信号转导途径，MCF-7乳腺癌细胞对抗癌药物的敏感性降低。
6. PIK3CA mutation confers resistance to chemotherapy in triple-negative breast cancer by inhibiting apoptosis and activating the PI3K/AKT/mTOR signaling pathway [O] . Huayu Hu, Junyong Zhu, Yuting Zhong, 2021

机译：Pik3CA突变通过抑制细胞凋亡并激活PI3K / AKT / MTOR信号传导途径来赋予三重阴性乳腺癌化疗的抵抗力
7. PI3K signaling pathway is activated by PIK3CA mRNA overexpression and copy gain in prostate tumors, but PIK3CA, BRAF, KRAS and AKT1 mutations are infrequent events [O] . Laia Agell, Silvia Hernández, Marta Salido, 2010

机译：PI3K信号通路通过Pik3Ca mRNA过表达和前列腺肿瘤复制增益激活，但Pik3Ca，BRAF，KRAS和AKT1突变是不常见的事件

Activation of the PI3K/AKT signalling pathway in non-melanoma skin cancer is not mediated by oncogenic PIK3CA and AKT1 hotspot mutations

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