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Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity

机译：Memantine的N-甲基-D-天冬氨酸（NMDA）反应的开放通道块：针对NMDA受体介导的神经毒性的治疗优势

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HS Chen; JW Pellegrini; SK Aggarwal; SZ Lei; S Warach; FE Jensen; SA Lipton;
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年度 1992
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1. Potency, voltage-dependency, agonist concentration-dependency, blocking kinetics and partial untrapping of the uncompetitive N-methyl-D-aspartate (NMDA) channel blocker memantine at human NMDA (GluN1/GluN2A) receptors. [J] . Gilling KE, Jatzke C, Hechenberger M, Neuropharmacology . 2009,第5期

机译：在人NMDA（GluN1 / GluN2A）受体上，非竞争性N-甲基-D-天冬氨酸（NMDA）通道阻断剂美金刚的效力，电压依赖性，激动剂浓度依赖性，阻断动力学和部分释放。
2. Alterations in expression of Cat-315 epitope of perineuronal nets during normal ageing, and its modulation by an open-channel NMDA receptor blocker, memantine [J] . Yamada Jun, Ohgomori Tomohiro, Jinno Shozo The Journal of Comparative Neurology . 2017,第9期

机译：正常老化期间猫-315表达猫-315表位的改变及其开放通道NMDA受体阻滞剂调节，Memantine
3. Neuroprotection by the NMDA receptor-associated open-channel blocker memantine in a photothrombotic model of cerebral focal ischemia in neonatal rat. [J] . Stieg PE, Sathi S, Warach S, European Journal of Pharmacology: An International Journal . 1999,第1a3期

机译：NMDA受体相关的开放通道阻滞剂美金刚胺在新生大鼠脑局灶性缺血的光血栓形成模型中的神经保护作用。
4. Blocking NMDA Mediated DYN Neurotoxicity Influences Brain Lipids Profile in Traumatic Brain Injury. [C] . Amina S. Woods, Shelley N Jackson, Aurelie Roux, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：阻断NMDA介导的DYN神经毒性会影响创伤性脑损伤中的脑脂质谱。
5. Memantine: Open-channel block of N-methyl-D-aspartate (NMDA) elicited responses. [D] . Chen, Huei-Sheng Vincent. 1992

机译：美金刚胺：N-甲基-D-天冬氨酸（NMDA）的开放通道阻滞引起反应。
6. Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity [O] . HS Chen, JW Pellegrini, SK Aggarwal, 1992

机译：美金刚胺对N-甲基-D-天冬氨酸（NMDA）反应的开放通道阻滞：对NMDA受体介导的神经毒性的治疗优势
7. Failures and Successes of NMDA Receptor Antagonists: Molecular Basis for the Use of Open-Channel Blockers like Memantine in the Treatment of Acute and Chronic Neurologic Insults [O] . Lipton, Stuart A. 2004

机译：NMDA受体拮抗剂的失败与成功：使用诸如美金刚这样的开放通道阻滞剂治疗急性和慢性神经损伤的分子基础

Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity

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