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Regulation of DNA Damage Following Termination of Hedgehog (HH) Survival Signaling at the level of the GLI Genes in Human Colon Cancer

机译：刺猬终止后的DNA损伤调节（HH）生存信号在人结肠癌的GLI基因水平下

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Akwasi Agyeman; Tapati Mazumdar; Janet A. Houghton;
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1. Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells. [J] . Mazumdar T, Devecchio J, Agyeman A, Cancer research: The official organ of the American Association for Cancer Research, Inc . 2011,第17期

机译：在GLI基因水平上阻断刺猬的生存信号，可诱导人结肠癌细胞中的DNA损伤和广泛的细胞死亡。
2. GSK3 beta and Gli3 play a role in activation of Hedgehog-Gli pathway in human colon cancer - Targeting GSK3 beta downregulates the signaling pathway and reduces cell proliferation [J] . Trnski Diana, Sabol Maja, Gojevic Ante, Biochimica et biophysica acta. Molecular basis of disease: BBA . 2015,第12期

机译：GSK3 beta和Gli3在人结肠癌的Hedgehog-Gli途径激活中起作用-靶向GSK3 beta下调信号通路并减少细胞增殖
3. Integrative genomic analyses on GLI1: Positive regulation of GLI1 by Hedgehog-GLI, TGFβ-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals [J] . Yuriko Katoh, Masaru Katoh International journal of oncology . 2009,第1期

机译：GLI1的整合基因组分析：Hedgehog-GLI，TGFβ-Smads和RTK-PI3K-AKT信号对GLI1的正调控，Notch-CSL-HES / HEY和GPCR-Gs-PKA信号对GLI1的负调控
4. Development of Multi-Null-Hypotheses Method for Detection of Selective Forces at Molecular Level in Evolution of Human Genes involved in DNA-Repair Mechanism Impaired in Cancer Progression [C] . Krzysztof A. Cyran, Marek Kimmel IFAC World Congress . 2014

机译：用于检测分子水平的多零假假设方法的癌症进展中DNA修复机制障碍中的人类基因演化中的选择性
5. Primary cilia mediate vertebrate Hedgehog signaling through the regulation of Smoothened and Gli2. [D] . Santos, Nicole M. 2012

机译：原发纤毛通过平滑化和Gli2的调节介导脊椎动物的刺猬信号。
6. Regulation of DNA Damage Following Termination of Hedgehog (HH) Survival Signaling at the level of the GLI Genes in Human Colon Cancer [O] . Akwasi Agyeman, Tapati Mazumdar, Janet A. Houghton 2012

机译：刺猬（HH）生存信号终止后人类结肠癌GLI基因水平对DNA损伤的调控
7. Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma Cells [O] . Tapati Mazumdar, Jennifer DeVecchio, Akwasi Agyeman, 2011

机译：在GLI基因水平下阻断刺猬生存信令在人结肠癌细胞中诱导DNA损伤和广泛的细胞死亡

Regulation of DNA Damage Following Termination of Hedgehog (HH) Survival Signaling at the level of the GLI Genes in Human Colon Cancer

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