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DNA repair-based classification of melanoma cell lines reveals an effect of mutations in BRAF and NRAS driver genes on DNA repair capacity

机译：基于DNA修复的黑素瘤细胞系的分类揭示了BRAF和NRAS驾驶基因对DNA修复能力的影响

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Sylvie Sauvaigo; Manel Benkhiat; Florian Braisaz; Julien Girard; Sarah Libert; Stéphane Mouret; Florence de Fraipont; Caroline Aspord; Fanny Bouquet; Marie-Thérèse Leccia;
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1. Clinicopathologic features and prognostic value of KRAS KRAS , NRAS NRAS and BRAF BRAF mutations and DNA mismatch repair status: A single‐center retrospective study of 1,834 Chinese patients with Stage I–IV colorectal cancer [J] . Guo Tian‐An, Wu Yu‐Chen, Tan Cong, International Journal of Cancer =: Journal International du Cancer . 2019,第6期

机译：KRAS KRAS，NRAS NRAS和BRAF BRAF突变和DNA错配修复状态的临床病理特征及预后价值：1,834例中国阶段I-IV型结直肠癌患者的单中心回顾性研究
2. Distinct patterns of DNA copy number alterations associate with BRAF mutations in melanomas and melanoma-derived cell lines. [J] . Greshock J, Nathanson K, Medina A, Genes, Chromosomes and Cancer . 2009,第5期

机译：DNA拷贝数变化的不同模式与黑色素瘤和黑色素瘤衍生的细胞系中的BRAF突变有关。
3. Illustrative cases for monitoring by quantitative analysis of BRAF/NRAS ctDNA mutations in liquid biopsies of metastatic melanoma patients who gained clinical benefits from anti-PD1 antibody therapy [J] . Seremet Teofila, Planken Simon, Schreuer Max, Melanoma research . 2018,第1期

机译：通过对抗PD1抗体治疗的临床益处的转移黑素瘤患者液体活组织检查中BRAF / NRAS CTDNA突变进行监测的说明性病例
4. MACHINE LEARNING FROM CONCEPT TO CLINIC: RELIABLE DETECTION OF BRAF V600E DNA MUTATIONS IN THYROID NODULES USING HIGH-DIMENSIONAL RNA EXPRESSION DATA [C] . JAMES DIGGANS, SU YEON KIM, ZHANZHI HU, Pacific Symposium on Biocomputing . 2015

机译：从概念到诊所的机器学习：使用高尺寸RNA表达数据可靠地检测甲状腺结节中的BRAF V600E DNA突变
5. NRAS and BRAF mutations in primary cutaneous melanoma: A comparison of mutation rates between radial and vertical growth phases in individual tumors. [D] . Greene, Victoria R. 2007

机译：原发性皮肤黑素瘤中的NRAS和BRAF突变：单个肿瘤在径向和垂直生长期之间的突变率比较。
6. Co-existence of BRAF and NRAS driver mutations in the same melanoma cells results in heterogeneity of targeted therapy resistance [O] . Marieke I. G. Raaijmakers, Daniel S. Widmer, Apurva Narechania, 2016

机译：同一黑色素瘤细胞中BRAF和NRAS驱动程序突变的共存导致靶向治疗耐药性的异质性
7. Co-existence of BRAF and NRAS driver mutations in the same melanoma cells results in heterogeneity of targeted therapy resistance [O] . Raaijmakers, Marieke I G, Widmer, Daniel S, Narechania, Apurva, 2016

机译：同一黑色素瘤细胞中BRAF和NRAS驱动程序突变的共存导致靶向治疗耐药性的异质性

DNA repair-based classification of melanoma cell lines reveals an effect of mutations in BRAF and NRAS driver genes on DNA repair capacity

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