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Peptide-Cleavable Self-immolative Maytansinoid Antibody–Drug Conjugates Designed To Provide Improved Bystander Killing

机译：肽可切割的自我牺牲的MAYONINOINOIN型抗体 - 药物缀合物旨在提供改善的旁观者杀伤

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Juliet A. Costoplus; Karen H. Veale; Qifeng Qiu; Jose F. Ponte; Leanne Lanieri; Yulius Setiady; Ling Dong; Anna Skaletskaya; Laura M. Bartle; Paulin Salomon; Rui Wu; Erin K. Maloney; Yelena V. Kovtun; Olga Ab; Kate Lai; Ravi V. J. Chari; Wayne C. Widdison;
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1. Peptide-Cleavable Self-immolative Maytansinoid Antibody-Drug Conjugates Designed To Provide Improved Bystander Killing [J] . Costoplus Juliet A., Veale Karen H., Qiu Qifeng, ACS medicinal chemistry letters . 2019,第10期

机译：肽可切割的自我牺牲的MASINOINOInoid抗体 - 药物缀合物，旨在提供改进的旁观者杀伤
2. Site-Specific Trastuzumab Maytansinoid Antibody-Drug Conjugates with Improved Therapeutic Activity through Linker and Antibody Engineering [J] . Thomas H. Pillow, Janet Tien, Kathryn L. Parsons-Reponte, Journal of Medicinal Chemistry . 2014,第19期

机译：特定部位的曲妥珠单抗美登木素生物碱抗体-药物通过接头和抗体工程结合起来具有改善的治疗活性
3. Antibody drug conjugates and bystander killing: is antigen-dependent internalisation required? [J] . Alexander H Staudacher, Michael P Brown British Journal of Cancer . 2017,第12期

机译：抗体药物偶联物和旁观者杀伤：是否需要抗原依赖性内在化作用？
4. Evaluation of the Relationship between Maytansinoid-to-Antibody Ratio and Maytansinoid Distribution Profile in Antibody-Maytansinoid Conjugates [C] . Megan Ellis, Lintao Wang, Alexandru C. Lazar, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2012

机译：评估抗体 - Maytansinoid缀合物中Maytansinoid-antidody比和Maytansinoid分布分布的关系
5. Improving Antibody-Drug Conjugate Tumor Distribution and Efficacy Using Single-Cell Imaging and Multiscale Modeling [D] . Cilliers, Cornelius 2018

机译：使用单细胞成像和多尺度建模改善抗体药物结合的肿瘤分布和功效
6. Peptide-Cleavable Self-immolative Maytansinoid Antibody–DrugConjugates Designed To Provide Improved Bystander Killing [O] . Juliet A. Costoplus, Karen H. Veale, Qifeng Qiu, 2019

机译：肽可裂解的自焚美登木素生物碱抗体-药物共轭设计旨在提供更好的旁观者杀戮
7. Design, synthesis and evaluation of anti-CD38 antibody drug conjugate based on Daratumumab and maytansinoid [O] . Xinfu Zhang, Chengxiang Zhang, Xiaomei Yang, 2019

机译：基于达拉姆法和美霉素的抗CD38抗体药物缀合物的设计，合成与评价

Peptide-Cleavable Self-immolative Maytansinoid Antibody–Drug Conjugates Designed To Provide Improved Bystander Killing

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