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A HER2-Targeting Antibody–Drug Conjugate, Trastuzumab Deruxtecan (DS-8201a), Enhances Antitumor Immunity in a Mouse Model

机译：HER2靶向抗体 - 药物缀合物，TRASTUZUMAB Deruxtecan（DS-8201A），增强了小鼠模型中的抗肿瘤免疫力

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Tomomi Nakayama Iwata; Chiaki Ishii; Saori Ishida; Yusuke Ogitani; Teiji Wada; Toshinori Agatsuma;
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年度 2018
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1. A HER2-Targeting Antibody-Drug Conjugate, Trastuzumab Deruxtecan (DS-8201a), Enhances Antitumor Immunity in a Mouse Model [J] . Iwata Tomomi Nakayama, Ishii Chiaki, Ishida Saori, Molecular cancer therapeutics . 2018,第7期

机译：HER2靶向抗体 - 药物缀合物TRASTUZUMAB Deruxtecan（DS-8201A），增强了小鼠模型中的抗肿瘤免疫力
2. Novel HER2-Targeting Antibody-Drug Conjugates of Trastuzumab Beyond T-DM1 in Breast Cancer: Trastuzumab Deruxtecan(DS-8201a) and (Vic-)Trastuzumab Duocarmazine (SYD985) [J] . Xu Zhuyu, Guo Dandan, Jiang Zhongliang, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2019,第期

机译：新的Her2-靶向抗体 - 药物缀合物的胸腺癌超出T-DM1的抗体 - 药物缀合物：曲妥珠胺Deruxtecan（DS-8201A）和（VIC-）曲妥珠单抗（SYD985）
3. Comprehensive preclinical pharmacokinetic evaluations of trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate, in cynomolgus monkeys [J] . Nagai Yoko, Oitate Masataka, Shiozawa Hideyuki, Xenobiotica: the fate of foreign compounds in biological systems . 2019,第7a12期

机译：Trastuzumab Deruxtecan（DS-8201A），一种靶向抗体 - 药物缀合物的综合临床前药代动力学评估，在Cynomolgus猴子中
4. QUANTIFICATION OF THE ANTIBODY DRUG CONJUGATE, TRASTUZUMAB EMTANSINE, AND THE MONOCLONAL ANTIBODY, TRASTUZUMAB, IN PLASMA USING A GENERIC KIT-BASED APPROACH [C] . Hua Yang, Mary Lame, Sherri Naughton, ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：使用通用套件的方法定量抗体药物缀合物，曲妥珠单抗蛋白和单克隆抗体，曲妥珠单抗，血浆中的血浆
5. Melatonin-Tamoxifen Drug Conjugates as Breast Cancer Drugs: Pharmacological Evaluation in Phenotypically Diverse Breast Cancer Models and Pharmacokinetic Assessment in Liver Microsome and Female Mouse Models [D] . Hasan, Mahmud. 2020

机译：褪黑激素 - 西昔芬药物缀合物作为乳腺癌药物：在肝微粒和女性小鼠模型中表型多种乳腺癌模型和药代动力学评估的药理评估
6. [Fam-] trastuzumab deruxtecan (DS-8201a)-induced antitumor immunity is facilitated by the anti–CTLA-4 antibody in a mouse model [O] . Tomomi Nakayama Iwata, Kiyoshi Sugihara, Teiji Wada, 2012

机译：[Fam-]曲妥珠单抗deruxtecan（DS-8201a）诱导的抗肿瘤免疫作用通过抗CTLA-4抗体在小鼠模型中促进
7. Fam- trastuzumab deruxtecan (DS-8201a)-induced antitumor immunity is facilitated by the anti–CTLA-4 antibody in a mouse model [O] . Tomomi Nakayama Iwata, Kiyoshi Sugihara, Teiji Wada, 2019

机译：通过小鼠模型中的抗CTLA-4抗体促进了抗肿瘤免疫诱导的抗肿瘤免疫力诱导的抗肿瘤免疫力

A HER2-Targeting Antibody–Drug Conjugate, Trastuzumab Deruxtecan (DS-8201a), Enhances Antitumor Immunity in a Mouse Model

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