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Design of recombinant protein-based SARS-CoV entry inhibitors targeting the heptad-repeat regions of the spike protein S2 domain

机译：基于重组蛋白的SARS-COV进入抑制剂的设计靶向穗蛋白S2结构域的七重复区域

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Ling Ni; Jieqing Zhu; Junjie Zhang; Meng Yan; George F. Gao; Po Tien;
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1. False-Positive Results in a Recombinant Severe Acute Respiratory Syndrome-Associated Coronavirus (SARS-CoV) Nucleocapsid-Based Western Blot Assay Were Rectified by the Use of Two Subunits (S1 and S2) of Spike for Detection of Antibody to SARS-CoV [J] . Mimoun Maache, Florence Komurian-Pradel, Alain Rajoharison, Clinical and vaccine immunology: CVI . 2006,第3期

机译：通过使用穗的两个亚基（S1和S2）检测SARS-CoV抗体，纠正了基于重组重症急性呼吸综合征的冠状病毒（SARS-CoV）基于核壳蛋白的Western印迹检测的假阳性结果。
2. Intranasal Vaccination of Recombinant Adeno-Associated Virus Encoding Receptor-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Spike Protein Induces Strong Mucosal Immune Responses and Provides Long-Term Protection against SARS-CoV Infection [J] . Lanying Du, Guangyu Zhao, Yongping Lin, The journal of immunology . 2008,第2期

机译：编码严重急性呼吸系统综合症冠状病毒（SARS-CoV）穗蛋白的受体结合域的重组腺相关病毒的鼻内接种疫苗诱导强烈的粘膜免疫反应并提供针对SARS-CoV感染的长期保护
3. Intranasal Vaccination of Recombinant Adeno-Associated Virus Encoding Receptor-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Spike Protein Induces Strong Mucosal Immune Responses and Provides Long-Term Protection against SARS-CoV Infection [J] . Lanying Du, Guangyu Zhao, Yongping Lin, The journal of immunology . 2008,第2期

机译：编码严重急性呼吸系统综合症冠状病毒（SARS-CoV）穗蛋白的受体结合域的重组腺相关病毒的鼻内接种疫苗诱导强烈的粘膜免疫反应并提供针对SARS-CoV感染的长期保护
4. Bispecific Antibodies Targeting the Ebola Glycoprotein Spike and Its Lysosomal Entry Receptor NPC1 Potently Inhibit Viral Infection [C] . Anna Wec, Elisabeth Nyakatura, Jonathan R. Lai, PEGS . 2015

机译：靶向埃博拉糖蛋白穗及其溶酶体进入受体NPC1的双特异性抗体有效地抑制病毒感染
5. Targeting IgV-like Domain Immune Checkpoint Receptors with Novel Nucleic Acid and Protein-based Therapeutics [D] . Prodeus, Aaron. 2018

机译：用新型核酸和基于蛋白质的治疗药物靶向IgV样域免疫检查点受体
6. Design of recombinant protein-based SARS-CoV entry inhibitors targeting the heptad-repeat regions of the spike protein S2 domain [O] . Ling Ni, Jieqing Zhu, Junjie Zhang, -1

机译：靶向穗蛋白S2结构域的七重复序列区域的基于重组蛋白的SARS-CoV进入抑制剂的设计
7. A single amino acid substitution in the S1 and S2 Spike protein domains determines the neutralization escape phenotype of SARS-CoV [O] . Yu-ya Mitsuki, Kazuo Ohnishi, Hirotaka Takagi, 2008

机译：S1和S2穗蛋白域中的单个氨基酸取代决定了SARS-COV的中和逃生表型
8. New Generic Method for the Production of Protein-Based Inhibitors of Proteins Involved in Cancer Metastasis [R] . Edgell, M. H. 1999

机译：用于产生基于蛋白质的蛋白质抑制剂的新通用方法涉及癌症转移

Design of recombinant protein-based SARS-CoV entry inhibitors targeting the heptad-repeat regions of the spike protein S2 domain

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