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Targeting Gys1 with AAV‐SaCas9 decreases pathogenic polyglucosan bodies and neuroinflammation in Adult Polyglucosan Body and Lafora disease mouse models

机译：用Aav-SACAS9靶向Gys1降低了成人聚葡聚糖体和Lafora疾病小鼠模型中的致病性聚葡聚糖体和神经炎炎症

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Emrah Gumusgoz; Dikran R Guisso; Sahba Kasiri; Jun Wu; Matthew Dear; Brandy Verhalen; Silvia Nitschke; Sharmistha Mitra; Felix Nitschke; Berge A. Minassian;
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1. GYS1 or PPP1R3C deficiency rescues murine adult polyglucosan body disease [J] . Erin E. Chown, Peixiang Wang, Xiaochu Zhao, Annals of Clinical and Translational Neurology . 2020,第11期

机译：Gys1或PPP1R3C缺乏救出鼠成人聚葡聚糖体疾病
2. POLYGLUCOSAN BODIES IN INTRAMUSCULAR NERVE BRANCHES ARE A POOR PREDICTOR OF GBE1 MUTATION AND ADULT POLYGLUCOSAN BODY DISEASE [J] . Furtado Larissa V., Kadri Sabah, Wurst Michelle N., Muscle and Nerve . 2016,第3期

机译：肌内神经分支中的多糖体是GBE1突变和成人多糖体病的不良预测指标
3. POLYGLUCOSAN BODIES IN INTRAMUSCULAR NERVE BRANCHES ARE A POOR PREDICTOR OF GBE1 MUTATION AND ADULT POLYGLUCOSAN BODY DISEASE [J] . Furtado Larissa V., Kadri Sabah, Wurst Michelle N., Muscle and Nerve . 2016,第3期

机译：肌内神经分支中的多糖体是GBE1突变和成人多糖体病的不良预测指标
4. Magnetoencephalography in Lafora body disease - a case report [C] . V. Pizzella, A. Verrolti, D. Trotta, International Conference on Biomagnetism . 2002

机译：Lafora Body疾病中的磁性脑膜 - 案例报告
5. Evaluating the Glycogenic Activity and Therapeutic Capacity of PPP1R3D in a Mouse Model of Lafora Disease [D] . Israelian, Lori 2018

机译：在Lafora病小鼠模型中评估PPP1R3D的糖原活性和治疗能力
6. GYS1 or PPP1R3C deficiency rescues murine adult polyglucosan body disease [O] . Erin E. Chown, Peixiang Wang, Xiaochu Zhao, 2020

机译：Gys1或PPP1R3C缺乏救出鼠成人聚葡聚糖体疾病
7. Laforin Prevents Stress-Induced Polyglucosan Body Formation and Lafora Disease Progression in Neurons [O] . Yin Wang, Keli Ma, Peixiang Wang, 2013

机译：Laforin防止胁迫诱导的聚葡聚糖体形成和Lafora病进展在神经元中

Targeting Gys1 with AAV‐SaCas9 decreases pathogenic polyglucosan bodies and neuroinflammation in Adult Polyglucosan Body and Lafora disease mouse models

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