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BRI2 Inhibits Amyloid -Peptide Precursor Protein Processing by Interfering with the Docking of Secretases to the Substrate

机译：Bri2通过干扰分泌凝血酶对基板的对接来抑制淀粉样蛋白 - 肽前体蛋白质处理

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S. Matsuda; L. Giliberto; Y. Matsuda; E. M. McGowan; L. DAdamio;
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年度 2008
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1. BRI2 inhibits amyloid beta-peptide precursor protein processing by interfering with the docking of secretases to the substrate. [J] . Matsuda S, Giliberto L, Matsuda Y, The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2008,第35期

机译：BRI2通过干扰分泌酶与底物的对接来抑制淀粉样β肽前体蛋白的加工。
2. The extracellular domain of Bri2 (ITM2B) binds the ABri peptide (1-23) and amyloid p-peptide (Apl-40): Implications for Bri2 effects on processing of amyloid precursor protein and Ap aggregation [J] . Siwei Peng, Michael Fitzen, Hans Jornvall, Biochemical and Biophysical Research Communications . 2010,第3期

机译：Bri2的胞外域（ITM2B）结合ABri肽（1-23）和淀粉样蛋白对肽（Apl-40）：Bri2对淀粉样前体蛋白加工和Ap聚集的影响
3. Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by γ-Secretase and Amyloid-β Peptide Production [J] . Hermeto Gerber, Fang Wu, Mitko Dimitrov, The Journal of biological chemistry . 2017,第9期

机译：锌和铜通过γ-分泌酶和β淀粉样肽生产差异调节淀粉样前体蛋白的加工。
4. Pharmacophore Based Virtual Screening, Molecular Docking and Density Functional Theory Approaches to Discover the Potent Beta-Amyloid Precursor Protein (B-App) Inhibitor [C] . G. Shakila, C. Meganathan, N. Sundaraganesan, National Conference on Hierarchically Structured Materials . 2019

机译：基于Pharmacophore的虚拟筛选，分子对接和密度泛函理论方法，以发现有效的β-淀粉样蛋白前体蛋白（B-APP）抑制剂
5. Familial Alzheimer's disease mutations decrease gamma-secretase processing of beta amyloid precursor protein. [D] . Wiley, Jesse Carey. 2003

机译：家族性阿尔茨海默氏病突变减少了β淀粉样蛋白前体蛋白的γ-分泌酶加工。
6. BRI2 Inhibits Amyloid β-Peptide Precursor Protein Processing by Interfering with the Docking of Secretases to the Substrate [O] . Shuji Matsuda, Luca Giliberto, Yukiko Matsuda, 2008

机译：BRI2通过干扰分泌酶对接底物来抑制淀粉样β肽前体蛋白加工。
7. BRI3 Inhibits Amyloid Precursor Protein Processing in a Mechanistically Distinct Manner from Its Homologue Dementia Gene BRI2* [O] . Matsuda, Shuji, Matsuda, Yukiko, D'Adamio, Luciano 2009

机译：BRI3以同源的痴呆症基因BRI2 *的方式在机械上截然不同的方式抑制淀粉样前体蛋白的加工*

BRI2 Inhibits Amyloid -Peptide Precursor Protein Processing by Interfering with the Docking of Secretases to the Substrate

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