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A Phase I Study of Single Administration of Antibody-Directed Enzyme Prodrug Therapy with the Recombinant Anti–Carcinoembryonic Antigen Antibody-Enzyme Fusion Protein MFECP1 and a Bis-Iodo Phenol Mustard Prodrug

机译：抗体介导的酶前体药物疗法的单次给药与重组抗胚抗原抗体 - 酶融合蛋白MFECP1和二碘酚芥菜前药I期研究

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Astrid Mayer; Roslyn J. Francis; Surinder K. Sharma; Berend Tolner; Caroline J. Springer; Jan Martin; Geoff M. Boxer; James Bell; Alan J. Green; John A. Hartley; Clare Cruickshank; Julie Wren; Kerry A. Chester; Richard H.J. Begent;
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1. Radiolabelling of glycosylated MFE-23::CPG2 fusion protein (MFECP1) with ~(99m)Tc for quantitation of tumour antibody-enzyme localisation in antibody-directed enzyme pro-drug therapy (ADEPT) [J] . R. J. Francis, S J. Mather, K. Chester, European journal of nuclear medicine . 2004,第8期

机译：用〜（99m）Tc对糖基化的MFE-23 :: CPG2融合蛋白（MFECP1）进行放射性标记，以定量抗体导向酶前药治疗（ADEPT）中的肿瘤抗体-酶定位
2. Design, construction, and in vitro analysis of A33scFv::CDy, a recombinant fusion protein for antibody-directed enzyme prodrug therapy in colon cancer [J] . Vania Coelho, Jens Dernedde, Ulf Petrausch, International journal of oncology . 2007,第4期

机译：设计，构建和体外分析A33scFv :: CDy，一种用于结肠癌抗体导向酶前药治疗的重组融合蛋白
3. Characterization of a CC49-Based Single-Chain Fragment-beta-Lactamase Fusion Protein for Antibody-Directed Enzyme Prodrug Therapy(ADEPT) [J] . Ralph F.Alderson, Brian E.Toki, Martin Roberge, Bioconjugate Chemistry . 2006,第2期

机译：基于CC49的单链片段-β-内酰胺酶融合蛋白的抗体定向酶前药治疗（ADEPT）的表征。
4. Short communication: A33scFv–cytosine deaminase: a recombinant protein construct for antibody-directed enzyme-prodrug therapy [O] . P M Deckert, C Renner, L S Cohen, 2003

机译：简短交流：A33scFv–胞嘧啶脱氨酶：用于抗体指导的酶-前药治疗的重组蛋白构建体
5. Short communication: A33scFv–cytosine deaminase: a recombinant protein construct for antibody-directed enzyme-prodrug therapy [O] . Deckert, P M, Renner, C, Cohen, L S, 2003

机译：简短交流：A33scFv–胞嘧啶脱氨酶：用于抗体指导的酶-前药治疗的重组蛋白构建体

A Phase I Study of Single Administration of Antibody-Directed Enzyme Prodrug Therapy with the Recombinant Anti–Carcinoembryonic Antigen Antibody-Enzyme Fusion Protein MFECP1 and a Bis-Iodo Phenol Mustard Prodrug

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