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Bispecific antibody target pair discovery by high-throughput phenotypic screening using in vitro combinatorial Fab libraries

机译：双特异性抗体通过体外组合Fab文库进行高通量表型筛选对靶对发现

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Pallavi Bhatta; Kevin D. Whale; Amy K. Sawtell; Clare L. Thompson; Stephen E. Rapecki; David A. Cook; Breda M. Twomey; Milena Mennecozzi; Laura E. Starkie; Emily M. C. Barry; Shirley J. Peters; Ahmad M. Kamal; Helene M. Finney;
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1. Construction of human combinatorial antibody library and screening of monoclonal antibody Fabs to human immunofeficiency virus type Ⅰ [J] . Wang Xue, He Yuxian, Zhou Ying Chinese science bulletin . 1999,第4期

机译：人组合抗体文库的构建及人免疫缺陷病毒Ⅰ型单克隆抗体Fabs的筛选
2. Format chain exchange (FORCE) for high-throughput generation of bispecific antibodies in combinatorial binder-format matrices [J] . Stefan Dengl, Klaus Mayer, Felix Bormann, Nature Communications . 2020,第1期

机译：用于组合粘合剂格式矩阵中双特异性抗体的高通量产生的格式链交换（力）
3. High-Throughput Purification of Combinatorial Libraries II:Automated Separation of Single Diastereomers from a 4-Amido-pyrrolidone Library Containing Intentional Diastereomer Pairs [J] . Mark Irving, Clinton A.Krueger, Janice V.Wade Journal of combinatorial chemistry . 2004,第4期

机译：组合库的高通量纯化II：自动从包含有意非对映异构体对的4-酰胺基-吡咯烷酮文库中分离单个非对映异构体
4. High-Throughput Flow Cytometric Screening of Combinatorial Chemistry Bead Libraries for Proteomics and Drug Discovery [C] . James F. Leary, Lisa M. Reece, Xianbin Yang, Advanced Biomedical and Clinical Diagnostic Systems III; Progress in Biomedical Optics and Imaging; vol.6 no.7 . 2005

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5. The Site-specific Modification of Therapeutic Proteins Produced in Escherichia coli: Implementation of a Combinatorial Bispecific Antibody Fragment Library Against Human Breast Carcinomas. [D] . Isett, Kevin D. 2010

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6. Discovery of Novel Anti-cryptosporidial Activities From Natural Products by in vitro High-Throughput Phenotypic Screening [O] . Zi Jin, Jingbo Ma, Guan Zhu, -1

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7. Antibiotic Discovery with Synthetic Fermentation: Library Assembly, Phenotypic Screening, and Mechanism of Action of Beta-Peptides Targeting Penicillin-Binding Proteins [O] . Iain A. Stepek, Trung Cao, Anika Koetemann, 2019

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Bispecific antibody target pair discovery by high-throughput phenotypic screening using in vitro combinatorial Fab libraries

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