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Copy-number analysis of topoisomerase and thymidylate synthase genes in frozen and FFPE DNAs of colorectal cancers

机译：结直肠癌冷冻和FFPE DNA中拓扑酶酶和胸苷合酶基因的复制数分析

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Jinsheng Yu; Ryan Miller; Wanghai Zhang; Mala Sharma; Vicky Holtschlag; Mark A Watson; Howard L McLeod;
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1. Copy-number analysis of topoisomerase and thymidylate synthase genes in frozen and FFPE DNAs of colorectal cancers [J] . Jinsheng Yu Ryan Miller Wanghai Zhang Mala Sharma Vicky Holtschlag Mark A Watson Howard L McLeod Pharmacogenomics . 2008,第10期

机译：大肠癌冷冻和FFPE DNA中拓扑异构酶和胸苷酸合酶基因的拷贝数分析
2. Polymorphisms in the enhancer region of the thymidylate synthase gene are associated with thymidylate synthase levels in normal tissues but not in malignant tissues of patients with colorectal cancer. [J] . Mauritz R, Giovannetti E, Beumer IJ, Clinical colorectal cancer . 2009,第3期

机译：胸苷酸合酶基因增强子区域的多态性与大肠癌患者正常组织中的胸苷酸合酶水平有关，而与大肠癌患者的恶性组织中无关。
3. Role of topoisomerase I and thymidylate synthase expression in sporadic colorectal cancer: Associations with clinicopathological and molecular features [J] . AzzoniC., BottarelliL., CecchiniS., Pathology Research and Practice . 2014,第2期

机译：拓扑异构酶I和胸苷酸合酶表达在散发性结直肠癌中的作用：与临床病理和分子特征的关联
4. Circulating Cell-Free DNA-Based qMSP Demonstrates That Sydecan2 Methylation as a Promising Epigenetic Biomarker for Early Detection of Patients with Precancerous and Cancerous Colorectal Lesions [C] . Sungwhan An, TaeJeong Oh, Dongjun Jeong, Molecular Medicine TRI-CON. . 2014

机译：循环无细胞的DNA基QMSP证明了Sydecan2甲基化作为有望的表观遗传生物标志物，用于早期检测患癌前和癌细胞病患者的患者
5. Evaluation of the accuracy of quantitative models in predicting Lynch syndrome (hereditary nonpolyposis colorectal cancer with defective DNA mismatch repair) mutations in a population-based sample of early-onset colorectal cancer patients [D] . Carpiniello, Lauren 2007

机译：在以人群为基础的早发性大肠癌患者样本中预测定量模型预测Lynch综合征（遗传性非息肉病性大肠直肠癌，DNA失配修复缺陷）的准确性
6. Copy-number analysis of topoisomerase and thymidylate synthase genes in frozen and FFPE DNAs of colorectal cancers [O] . Jinsheng Yu, Ryan Miller, Wanghai Zhang, -1

机译：大肠癌冷冻和FFPE DNA中拓扑异构酶和胸苷酸合酶基因的拷贝数分析
7. Topoisomerase I but not thymidylate synthase is associated with improved outcome in patients with resected colorectal cancer treated with irinotecan containing adjuvant chemotherapy [O] . 2009

机译：在接受伊立替康辅助化疗的结直肠癌切除患者中，拓扑异构酶I而非胸苷酸合酶可改善结局

Copy-number analysis of topoisomerase and thymidylate synthase genes in frozen and FFPE DNAs of colorectal cancers

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