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Crystallographic Approach to Identification of Cyclin-dependent Kinase 4 (CDK4)-specific Inhibitors by Using CDK4 Mimic CDK2 Protein

机译：用CDK4模拟CDK2蛋白来鉴定细胞周期蛋白依赖性激酶4（CDK4）抑制剂的结晶方法

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Mari Ikuta; Kenji Kamata; Kazuhiro Fukasawa; Teruki Honma; Takumitsu Machida; Hiroshi Hirai; Ikuko Suzuki-Takahashi; Takashi Hayama; Susumu Nishimura;
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年度 2001
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1. Understanding and modulating cyclin-dependent kinase inhibitor specificity: molecular modeling and biochemical evaluation of pyrazolopyrimidinones as CDK2/cyclin A and CDK4/cyclin D1 inhibitors [J] . Rossi KA, Markwalder JA, Seitz SP, Journal of Computer-Aided Molecular Design . 2005,第2期

机译：了解和调节细胞周期蛋白依赖性激酶抑制剂的特异性：作为CDK2 / cyclin A和CDK4 / cyclin D1抑制剂的吡唑并嘧啶酮的分子模型和生化评估
2. INHIBITION STUDIES OF TERPENE BASED NATURAL PRODUCTS WITH CYCLIN-DEPENDENT KINASE 4 (CDK4 MIMIC CDK2) [J] . Sunil H. Ganatra, Amita S. Suchak International Journal of Pharmaceutical Sciences and Research . 2012,第9期

机译：萜类依赖性激酶4（CDK4 MIMIC CDK2）对基于萜烯的天然产物的抑制研究
3. INHIBITION STUDIES OF TERPENE BASED NATURAL PRODUCTS WITH CYCLIN-DEPENDENT KINASE 4 (CDK4 MIMIC CDK2) [J] . Sunil H. Ganatra, Amita S. Suchak International Journal of Pharmaceutical Sciences and Research . 2012,第9期

机译：萜类依赖性激酶4（CDK4 MIMIC CDK2）对基于萜烯的天然产物的抑制研究
4. Study of a ligand complexed with Cdk2/Cdk4 by computer simulation [C] . Yongjun Jiang, Jiaimei Zou, Chunshan Gui 第三届国际分子模拟与信息技术应用学术会议 . 2007

机译：通过计算机模拟研究与Cdk2 / Cdk4络合的配体
5. Development of a Chemoproteomic Approach to Study Kinase-Substrate Interactions and the Discovery of CDK4 as a 4E-BP1 Kinase [D] . Mitchell, Dylan Charles. 2019

机译：化学研究方法研究激酶-底物相互作用和发现CDK4作为4E-BP1激酶的发展。
6. HTLV-1 Tax protein interacts with cyclin-dependent kinase inhibitor p16INK4A and counteracts its inhibitory activity towards CDK4. [O] . T Suzuki, S Kitao, H Matsushime, 1996

机译：HTLV-1 Tax蛋白与细胞周期蛋白依赖性激酶抑制剂p16INK4A相互作用并抵消其对CDK4的抑制活性。
7. Estrogen-induced Activation of Cdk4 and Cdk2 during G1-S Phase Progression Is Accompanied by Increased Cyclin D1 Expression and Decreased Cyclin-dependent Kinase Inhibitor Association with Cyclin E-Cdk2 [O] . OwenW. J. Prall, Boris Sarcevic, Elizabeth A. Musgrove, 1997

机译：在G1-S期进展期间雌激素诱导的CDK4和CDK2活化伴随着与细胞周期蛋白E-CDK2的细胞周期蛋白D1表达和细胞周期蛋白依赖性激酶抑制剂联合增加
8. Structure-Based Design of Cdk4/6-Specific Inhibitors [R] . Marmorstein, R. 2006

机译：基于结构的Cdk4 / 6特异性抑制剂设计

Crystallographic Approach to Identification of Cyclin-dependent Kinase 4 (CDK4)-specific Inhibitors by Using CDK4 Mimic CDK2 Protein

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