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Effects of Mutations in the Receptor-Binding Domain of SARS-CoV-2 Spike on its Binding Affinity to ACE2 and Neutralizing Antibodies Revealed by Computational Analysis

机译：SARS-COV-2穗对受体结合结构域突变对其对ace2和中和抗体进行计算分析的影响

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Marine E. Bozdaganyan; Olga S. Sokolova; Konstantin V. Shaitan; Mikhail P. Kirpichnikov; Philipp S. Orekhov;
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1. Competitive SARS-CoV-2 Serology Reveals Most Antibodies Targeting the Spike Receptor-Binding Domain Compete for ACE2 Binding [J] . James R. Byrnes, Xin X. Zhou, Irene Lui, mSphere . 2020,第5期

机译：竞争性SARS-COV-2血清学揭示了大多数抗体，靶向尖峰受体结合结构域竞争ACE2结合
2. Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains [J] . Zhou Tongqing, Tsybovsky Yaroslav, Gorman Jason, Cell Host & Microbe . 2020,第6期

机译：SARS-COV-2穗的Cryo-EM结构没有和ACE2显示pH依赖性开关，以介导受体结合结构域的内体定位
3. Computational simulations reveal the binding dynamics between human ACE2 and the receptor binding domain of SARS-CoV-2 spike protein [J] . Lupala Cecylia S., Li Xuanxuan, Lei Jian, Quantitative biology . 2021,第1期

机译：计算模拟显示人ACE2和SARS-COV-2穗蛋白的受体结合结构域之间的结合动态
4. Analysis of SARS-CoV-2 sequences reveals transmission path and emergence of SD 614G mutation. [C] . Mingjia Li, Nishita Prasad, Dwight Hall, IEEE International Conference on Bioinformatics and Biomedicine . 2020

机译：SARS-COV-2序列的分析显示了SD 614G突变的传输路径和出现。
5. Genetic engineering of two Escherichia coli strains designed to bioaccumulate copper and cadmium: Construction, characterization, and mutational analysis of key regions involved in high affinity metal binding. [D] . Zagorski, Nicholas. 2003

机译：设计用于生物积累铜和镉的两种大肠杆菌菌株的基因工程：涉及高亲和力金属结合的关键区域的构建，表征和突变分析。
6. Effect of An 84-bp Deletion of the Receptor-Binding Domain on the ACE2 Binding Affinity of the SARS-CoV-2 Spike Protein: An In Silico Analysis [O] . Gábor Kemenesi, Gábor Endre Tóth, Dávid Bajusz, 2021

机译：84bp缺失对受体结合结构域对SARS-COV-2穗蛋白的ACE2结合亲和力的影响：在硅分析中
7. Effect of An 84-bp Deletion of the Receptor-Binding Domain on the ACE2 Binding Affinity of the SARS-CoV-2 Spike Protein: An In Silico Analysis [O] . Gábor Kemenesi, Gábor Endre Tóth, Dávid Bajusz, 2021

机译：84bp缺失对受体结合结构域对SARS-COV-2穗蛋白的ACE2结合亲和力的影响：在硅分析中

Effects of Mutations in the Receptor-Binding Domain of SARS-CoV-2 Spike on its Binding Affinity to ACE2 and Neutralizing Antibodies Revealed by Computational Analysis

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