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Respiratory health effects of the fiberglass-reinforced plastic lamination process in the yacht-building industry

机译:游艇建筑业玻璃纤维增​​强塑料层压工艺的呼吸系统效应

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摘要

OBJECTIVES: Fiberglass-reinforced plastics (FRP) manufacturing has been related to cases of severe airway obstruction and elevated risk of respiratory mortality. But the specific job content risk is not clear. This study evaluated the respiratory health effects of the FRP lamination process. METHODS: A questionnaire was used to evaluate respiratory symptoms of workers in two yacht-building plants. Pre-shift (07:30–08:30 hours) and post-shift (17:00–18:00 hours) lung function was measured, while post-shift induced sputum was collected on the first day of the week. The participants were grouped into FRP laminators and non-laminators. Linear and logistic regression was used to investigate the effects of the lamination process on lung function. RESULTS: Laminators had a higher prevalence of chronic cough, lower pre-shift forced expiratory volume in first second (FEV1) and FEV1/force vital capacity (FVC) (-3.3% and -1.5%), lower post-shift FVC and FEV1 (-3.6% and -4.9%), and larger post-shift reduction of FVC (-2.1%) compared to non-laminators. The laminators also had higher risk of early obstructive and overall (obstructive plus restrictive) lung function impairment, and post-shift reduction of FVC >10% [odds ratio (OR) 5.98, 4.98, and 3.87, respectively). They also had higher percentages of neutrophils and lymphocytes in the induced sputum. CONCLUSION: Laminators should undergo regular check-ups of respiratory symptoms and lung function. Further toxicologic studies are warranted to identify the specific causal agent in the FRP lamination process.
机译:目的:玻璃纤维增​​强塑料(FRP)的制造已经涉及到严重的气道阻塞的情况,并提高呼吸系统死亡的风险。但具体的工作内容的风险是不明确的。这项研究评估的FRP层压工艺的呼吸健康的影响。方法:问卷被用来评估两个游艇建造厂工人的呼吸道症状。预切换(07:30-08:30小时)和后移(17:00-18:00小时)肺功能进行测定,同时后移位诱导痰收集在一周的第一天。参与者被分为玻璃钢层压机和非层压。线性和逻辑回归被用于研究层压过程对肺功能的影响。结果:层合有慢性咳嗽的发病率较高,较低的预切换被迫在第一第二(FEV1)和FEV1 /力肺活量(FVC)呼气量(-3.3%和-1.5%),低级后移FVC和FEV1 (-3.6%-4.9和%),并与非层压FVC(-2.1%)的较大的后移减少。该层合机还具有早期阻塞性和整体(阻塞性加上限制性的)肺功能受损的风险较高,和FVC的后移减少> 10%[比值比(OR)5.98,4.98,和3.87,分别地)。他们也有在诱导痰嗜中性粒细胞和淋巴细胞的比例较高。结论:层压机应该接受的呼吸道症状和肺功能定期检查。此外毒理学研究是必要的,以确定在FRP层压过程的特定致病因子。

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