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Mice lacking the transcobalamin-vitamin B12 receptor, CD320, suffer from anemia and reproductive deficits when fed vitamin B12-deficient diet

机译：小鼠缺乏转基质 - 维生素B12受体，CD320，当喂养维生素B12缺陷饮食时患有贫血和生殖缺陷

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David J Bernard; Faith J Pangilinan; Jun Cheng; Anne M Molloy; Lawrence C Brody;
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1. Mice lacking the transcobalamin-vitamin B12 receptor, CD320, suffer from anemia and reproductive deficits when fed vitamin B12-deficient diet [J] . Bernard David J., Pangilinan Faith J., Cheng Jun, Human Molecular Genetics . 2018,第20期

机译：小鼠缺乏转基质 - 维生素B12受体，CD320，当喂养维生素B12缺陷饮食时患有贫血和生殖缺陷
2. Effect of Weight-Reduction in Obese Mice Lacking Toll-Like Receptor 5 and C57BL/6 Mice Fed a Low-Fat Diet [J] . Shao-ChunWu, Cheng-ShyuanRau, Tsu-HsiangLu, Mediators of inflammation . 2015,第1期

机译：减肥对缺乏低脂饮食的肥胖小鼠缺乏Toll样受体5和C57BL / 6小鼠的影响
3. Effect of Weight-Reduction in Obese Mice Lacking Toll-Like Receptor 5 and C57BL/6 Mice Fed a Low-Fat Diet [J] . Wu Shao-Chun, Rau Cheng-Shyuan, Lu Tsu-Hsiang, Mediators of inflammation . 2015,第8期

机译：减肥在缺乏Toll样受体5和C57BL / 6小鼠喂养低脂饮食的肥胖小鼠的影响
4. An investigation of the effects of vitamin E succinate (VES) on human prostate LNCaP tumor growth and gene expression in BALB/c nude mice fed high-fat diets. [D] . Aredo, Bogale. 2011

机译：研究维生素E琥珀酸酯（VES）对高脂饮食喂养的BALB / c裸鼠中人前列腺LNCaP肿瘤生长和基因表达的影响。
5. Mice lacking the transcobalamin-vitamin B12 receptor CD320 suffer from anemia and reproductive deficits when fed vitamin B12-deficient diet [O] . David J Bernard, Faith J Pangilinan, Jun Cheng, -1

机译：缺乏维生素B12缺乏饮食的小鼠缺乏跨钴胺素维生素B12受体CD320患有贫血和生殖缺陷
6. Six practical diets were formulated to contain 2.6 (the basal diet), 48.9, 95.5, 189.83, 382.4, 779.53 mg/kg vitamin C diet. After 8 weeks of feeding, growth performance, antioxidant status, and innate immunity of juvenile pufferfish were analyzed. Results showed that specific growth rate and protein efficiency ratio in fish fed diets supplemented with vitamin C were significantly higher than in fish fed the control diet. Dietary vitamin C significantly up-regulated the expression levels of growth hormone receptors and Insulin-like growth factor. Blood cell numbers and respiratory burst activity were enhanced in fish fed vitamin C diet. Serum alkaline phosphatase, glutamic-pyruvic transaminase, and glutamic-oxaloacetic transaminase activity were significantly influenced by the dietary vitamin C levels. Fish fed diets supplemented with vitamin C showed increased hepatic superoxide dismutase, glutathione peroxidase, and catalase activity, but decreased malondialdehyde activity. In addition, we found that dietary vitamin C can significantly up-regulate the expression levels of immune-related genes (HSP70, HSP90, BAFF, TNF-α and IL-6) in liver. These results indicate that dietary vitamin C can significantly influence growth performance, antioxidant status, and innate immunity of pufferfish. [O] . Cheng C-H, Liang H-Y., Guo Z-X., 2017

机译：配制了六种实用饮食，分别含有2.6（基础饮食），48.9、95.5、189.83、382.4、779.53 mg / kg维生素C饮食。喂食8周后，分析了幼崽河豚的生长性能，抗氧化剂状态和先天免疫力。结果表明，补充维生素C的鱼饲料的比生长速率和蛋白质效率比显着高于对照组的鱼。饮食中的维生素C显着上调了生长激素受体和胰岛素样生长因子的表达水平。喂鱼的维生素C饮食可提高血细胞数量和呼吸爆发活性。饮食中的维生素C水平显着影响血清碱性磷酸酶，谷氨酸-丙酮酸转氨酶和谷氨酸-草酰乙酸转氨酶的活性。补充维生素C的鱼饲料日粮中肝超氧化物歧化酶，谷胱甘肽过氧化物酶和过氧化氢酶活性增加，但丙二醛活性降低。此外，我们发现饮食中的维生素C可以显着上调肝脏中免疫相关基因（HSP70，HSP90，BAFF，TNF-α和IL-6）的表达水平。这些结果表明，饮食中的维生素C可以显着影响河豚的生长性能，抗氧化状态和先天免疫力。

Mice lacking the transcobalamin-vitamin B12 receptor, CD320, suffer from anemia and reproductive deficits when fed vitamin B12-deficient diet

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