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Low Density Lipoprotein Binds to Proprotein Convertase Subtilisin/Kexin Type-9 (PCSK9) in Human Plasma and Inhibits PCSK9-mediated Low Density Lipoprotein Receptor Degradation

机译：低密度脂蛋白与人血浆中的ProProtein转化酶枯草杆菌蛋白酶/ kexin型-9（PCSK9）结合，抑制PCSK9介导的低密度脂蛋白受体降解

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Tanja Kosenko; Mia Golder; Geoffrey Leblond; Willy Weng; Thomas A. Lagace;
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1. Serum levels of proprotein convertase subtilisin/kexin type 9 in subjects with familial hypercholesterolemia indicate that proprotein convertase subtilisin/kexin type 9 is cleared from plasma by low-density lipoprotein receptor-independent pathways [J] . CameronJ., BogsrudM.P., TvetenK., Translational research: the journal of laboratory and clinical medicine . 2012,第2期

机译：家族性高胆固醇血症患者的血清原蛋白转化酶枯草杆菌蛋白酶/ kexin 9型水平表明通过低密度脂蛋白受体非依赖性途径从血浆中清除了原蛋白转化酶枯草杆菌蛋白酶/ kexin 9型
2. A Proprotein Convertase Subtilisin-like/Kexin Type 9 (PCSK9) C-terminal Domain Antibody Antigen-binding Fragment Inhibits PCSK9 Internalization and Restores Low Density Lipoprotein Uptake [J] . Yan Ni, Jon Condra, Laura Orsatti, The Journal of biological chemistry . 2010,第17期

机译：ProProtein转化酶枯草杆菌蛋白酶样/ kexin型9（PCSK9）C-末端域抗体抗原结合片段抑制PCSK9内化并恢复低密度脂蛋白摄取
3. Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor) [J] . Ouadda Ali Ben Djoudi, Gauthier Marie-Soleil, Susan-Resiga Delia, Arteriosclerosis, thrombosis, and vascular biology . 2019,第10期

机译：PCSK9（Proprotein转化酶枯草杆菌蛋白酶-Kexin 9）的Ser-磷酸化通过FAM20C（具有序列相似性20，成员C）激酶增强其降解LDLR的能力（低密度脂蛋白受体）
4. Role of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 (LOX-1) in Adenosine Diphosphate-Activated Platelet Adhesion to Human Brain Microvascular Endothelial Cells Under Flow In Vitro [C] . Norio Tanahashi, Yoshiaki ItohMIideki Satoh, Takato Abe, Keio International Symposia for Life Sciences and Medicine . 2005

机译：凝集素样氧化低密度脂蛋白受体-1（LOX-1）在体外流量下对人脑微血管内皮细胞的腺苷二磷酸活性血小板粘附的作用
5. Class B scavenger receptors: Metabolism of high density lipoprotein and oxidized low density lipoprotein [D] . Sun, Bing 2006

机译：B类清道夫受体：高密度脂蛋白和氧化型低密度脂蛋白的代谢
6. Low Density Lipoprotein Binds to Proprotein Convertase Subtilisin/Kexin Type-9 (PCSK9) in Human Plasma and Inhibits PCSK9-mediated Low Density Lipoprotein Receptor Degradation [O] . Tanja Kosenko, Mia Golder, Geoffrey Leblond, 2013

机译：低密度脂蛋白与人血浆中的前蛋白转化酶枯草杆菌蛋白酶/ Kexin 9型（PCSK9）结合并抑制PCSK9介导的低密度脂蛋白受体降解
7. A Proprotein Convertase Subtilisin-like/Kexin Type 9 (PCSK9) C-terminal Domain Antibody Antigen-binding Fragment Inhibits PCSK9 Internalization and Restores Low Density Lipoprotein Uptake [O] . Ni, Yan G., Condra, Jon H., Orsatti, Laura, 2010

机译：前蛋白转化酶枯草杆菌蛋白酶样/ Kexin 9型（PCSK9）C端域抗体抗原结合片段抑制PCSK9内化并恢复低密度脂蛋白摄取。

Low Density Lipoprotein Binds to Proprotein Convertase Subtilisin/Kexin Type-9 (PCSK9) in Human Plasma and Inhibits PCSK9-mediated Low Density Lipoprotein Receptor Degradation

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