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61. Ascending Dose Trials of a Retroviral Replicating Vector (Toca 511) in Patients with Recurrent High-Grade Glioma: Clinical Update, Molecular Analyses, and Proposed Mechanism of Action

机译：61.复制高级胶质瘤患者逆转录病毒复制载体（TOCA 511）的升序剂量试验：临床更新，分子分析和提出的作用机制

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Douglas J. Jolly; Joan M. Robbins; Derek Ostertag; Carlos Ibañez; Noriyuki Kasahara; Harry Gruber; Steven N. Kalkanis; Michael Vogelbaum; Manish K. Aghi; Timothy Cloughesy; Alice Chu; Asha Das; Jamey Skillings;
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1. Clinical update, molecular analyses, and proposed mechanism of action of Toca 511 a retroviral replicating vector in three ascending dose trials in patients with recurrent high-grade glioma [J] . Jolly D. J., Ostertag D., Hogan D., Human gene therapy . 2016,第11期

机译：Toca 511（逆转录病毒复制载体）在复发性高级别胶质瘤患者的三项递增剂量试验中的临床更新，分子分析和拟议的作用机制
2. Molecular Analyses Support the Safety and Activity of Retroviral Replicating Vector Toca 511 in Patients [J] . Hogan Daniel J., Zhu Jay-Jiguang, Diago Oscar R., Clinical cancer research: an official journal of the American Association for Cancer Research . 2018,第19期

机译：分子分析支持患者逆转录病毒复制载体TOCA 511的安全性和活性
3. LONG-TERM FOLLOW-UP DATA FROM 126 PATIENTS WITH RECURRENT HIGH GRADE GLIOMA FROM THREE PHASE 1 TRIALS OF TOCA 511 AND TOCA FC: UPDATE AND JUSTIFICATION FOR A PHASE 2/3 TRIAL [J] . Aghi M., Vogelbaum M. A., Kalkanis S. N., Neuro-Oncology . 2017,第MAySuppla3期

机译：来自TOCA 511和TOCA FC的三个第1阶段试验的126例复发性高度胶质瘤患者的长期随访数据：第2/3阶段试验的更新和合理性
4. DDEL-06PRELIMINARY SAFETY OF TOCA 511 A RETROVIRAL REPLICATING VECTOR IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA ACROSS THREE SEPARATE PHASE 1 STUDIES [O] . Steven N. Kalkanis, Manish K. Aghi, Timothy F. Cloughsy, 2015

机译：DDEL-06 TOCA 511（一种替代药物的翻新矢量）在三项单独的第1阶段研究中均出现复发性高度胶质瘤的患者的安全性
5. 28. Interim Report from Two Ongoing Ascending Dose Trials of a Retroviral Replicating Vector (Toca 511) in Patients with Recurrent High Grade Glioma [O] . 2014

机译：28.从复发性高级胶质瘤患者的逆转录病毒复制载体（TOCA 511）的两次持续升序剂量试验中的临时报告

61. Ascending Dose Trials of a Retroviral Replicating Vector (Toca 511) in Patients with Recurrent High-Grade Glioma: Clinical Update, Molecular Analyses, and Proposed Mechanism of Action

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