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Chemical Synthesis and Biological Activities of 20S,24S/R-Dihydroxyvitamin D3 Epimers and Their 1α-Hydroxyl Derivatives

机译：20s，24s / R-二羟基维生素D3映射和其1α-羟基衍生物的化学合成和生物活性

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Zongtao Lin; Srinivasa Reddy Marepally; Dejian Ma; Linda K. Myers; Arnold E. Postlethwaite; Robert C. Tuckey; Chloe Y. S. Cheng; Tae-Kang Kim; Junming Yue; Andrzej T. Slominski; Duane D. Miller; Wei Li;
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1. Chemical Synthesis and Biological Activities of 205,24S/R-Dihydroxyvitamin D3 Epimers and Their 1 alpha-Hydroxyl Derivatives [J] . Lin Zongtao, Marepally Srinivasa Reddy, Ma Dejian, Journal of Medicinal Chemistry . 2015,第19期

机译：205,24S / R-二羟基维生素D3差向异构体及其1α-羟基衍生物的化学合成及生物活性
2. Enhanced biological activity of 1alpha,25-dihydroxy-20-epi-vitamin D3, the C-20 epimer of 1alpha,25-dihydroxyvitamin D3, is in part due to its metabolism into stable intermediary metabolites with significant biological activity. [J] . Siu Caldera-ML, Sekimoto H, Peleg S, The Journal of Steroid Biochemistry and Molecular Biology . 1999,第3a4期

机译：1alpha，25-dihydroxy-20-epi-vitamin D3（1alpha，25-dihydroxyvitamin D3的C-20差向异构体）的增强的生物活性部分是由于其代谢为具有重要生物学活性的稳定的中间代谢产物。
3. Synthesis and Biological Evaluation of Vitamin D3 Metabolite 20S,23S-Dihydroxyvitamin D3 and Its 23R Epimer [J] . Lin Zongtao, Marepally Srinivasa R., Ma Dejian, Journal of Medicinal Chemistry . 2016,第10期

机译：维生素D3代谢物20S，23S-二羟基维生素D3及其23R差向异构体的合成及生物学评价
4. Synthesis and Radical Scavenging Activity of 6-Hydroxyl-4-Methylcoumarin and Its Derivatives [C] . Juliana Jumal, Adetunji Fridaos Ayomide International Conference on Recent Advancements in Science and Technology . 2017

机译：6-羟基-4-甲基豆素及其衍生物的合成和自由基清除活性
5. Studies in synthetic organic chemistry: Part I. The synthesis of novel antimalarial artmeisinin dimers. Part II. Electronically stabilized versions of antimalarial acetal trioxanes. Part III. Novel analogs of natural hormone 1-alpha, 25-dihdroxyvitamin D3: Design, synthesis and biological evaluation of CYP24 inhibitors. Part IV. New silicon mediated ring expansions of N-sized 2-cycloalkenones into homoallylic N+3 sized lactones. [D] . Kalinda, Alvin Solomon. 2009

机译：合成有机化学研究：第一部分。新型抗疟药青蒿素二聚体的合成。第二部分电子稳定版的抗疟缩醛三恶烷。第三部分天然激素1-α，25-二羟维生素D3的新型类似物：CYP24抑制剂的设计，合成和生物学评估。第四部分新的硅介导的N尺寸的2-环烯酮的环扩环成均烯丙基N + 3尺寸的内酯。
6. Chemical Synthesis and Biological Activities of 20S24S/R-Dihydroxyvitamin D3 Epimers and Their 1α-Hydroxyl Derivatives [O] . Zongtao Lin, Srinivasa Reddy Marepally, Dejian Ma, -1

机译：20S24S / R-二羟基维生素D3差向异构体及其1α-羟基衍生物的化学合成及生物活性
7. Synthesis and biological evaluation of all A-ring stereoisomers of 5,6-trans-2-methyl-1,25-dihydroxyvitamin D3 and their 20-epimers: possible binding modes of potent A-ring analogues to vitamin D receptor [O] . Fujishima Toshie, Konno Katsuhiro, Nakagawa Kimie, 2001

机译：5,6-反-2-甲基-1,25-二羟基维生素D3及其20个受体的所有A环立体异构体的合成和生物学评估：有效的A环类似物与维生素D受体的可能结合方式

Chemical Synthesis and Biological Activities of 20S,24S/R-Dihydroxyvitamin D3 Epimers and Their 1α-Hydroxyl Derivatives

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