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Defective DNA repair increases susceptibility to senescence through extension of Chk1-mediated G2 checkpoint activation

机译：DNA修复有缺陷的DNA修复通过延长CHK1介导的G2检查点激活来增加对衰老的敏感性

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Yoshikazu Johmura; Emiri Yamashita; Midori Shimada; Keiko Nakanishi; Makoto Nakanishi;
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1. Defective DNA repair increases susceptibility to senescence through extension of Chk1-mediated G2 checkpoint activation [J] . Yoshikazu Johmura, Emiri Yamashita, Midori Shimada, Scientific reports. . 2016,第1期

机译：DNA修复有缺陷的DNA修复通过延长CHK1介导的G2检查点激活来增加对衰老的敏感性
2. High osmolality activates the G1 and G2 cell cycle checkpoints and affects the DNA integrity of nucleus pulposus intervertebral disc cells triggering an enhanced DNA repair response. [J] . Mavrogonatou E, Kletsas D DNA repair . 2009,第8期

机译：高渗透压激活G1和G2细胞周期检查点，并影响髓核椎间盘细胞的DNA完整性，从而触发增强的DNA修复反应。
3. The p38 Mitogen-Activated Protein Kinase Pathway Links the DNA Mismatch Repair System to the G2 Checkpoint and to Resistance to Chemotherapeutic DNA-Methylating Agents [J] . Yuichi Hirose, Makoto Katayama, David Stokoe, Molecular and Cellular Biology . 2003,第22期

机译：p38丝裂原激活的蛋白激酶途径将DNA错配修复系统连接至G2检查点，并具有对化疗DNA-甲基化剂的抗性
4. Robustness of CDK2 in triggering cellular senescence based on probability of DNA-damaged cells passing G1/S checkpoint [C] . Ling Hong, Samarasinghe Sandhya, Kulasiri Don 2011 IEEE International Conference on Systems Biology . 2011

机译：基于DNA损伤的细胞通过G1 / S检查点的概率，CDK2在触发细胞衰老中的鲁棒性
5. Studies of the cell cycle regulation of checkpoint activation and DNA double -strand break repair in Saccharomyces cerevisiae. [D] . Barlow, Jacqueline. 2008

机译：酿酒酵母中检查点激活和DNA双链断裂修复的细胞周期调控研究。
6. Defective DNA repair increases susceptibility to senescence through extension of Chk1-mediated G2 checkpoint activation [O] . Yoshikazu Johmura, Emiri Yamashita, Midori Shimada, -1

机译：DNA缺陷修复通过延长Chk1介导的G2检查点激活而增加了对衰老的敏感性
7. The p38 Mitogen-Activated Protein Kinase Pathway Links the DNA Mismatch Repair System to the G2 Checkpoint and to Resistance to Chemotherapeutic DNA-Methylating Agents [O] . Hirose, Yuichi, Katayama, Makoto, Stokoe, David, 2003

机译：p38丝裂原激活的蛋白激酶途径将DNA错配修复系统连接至G2检查点，并具有对化疗DNA-甲基化剂的抗性

Defective DNA repair increases susceptibility to senescence through extension of Chk1-mediated G2 checkpoint activation

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