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Antitumor Synergism and Enhanced Survival with a Tumor Vasculature–Targeted Enzyme Prodrug System, Rapamycin, and Cyclophosphamide

机译：抗肿瘤协同作用和增强的生存与肿瘤血管有针对性的酶前药系统，雷帕霉素和环磷酰胺

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John J. Krais; Needa Virani; Patrick H. McKernan; Quang Nguyen; Kar-Ming Fung; Vassilios I. Sikavitsas; Carla Kurkjian; Roger G. Harrison;
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1. Antitumor Synergism and Enhanced Survival with a Tumor Vasculature-Targeted Enzyme Prodrug System, Rapamycin, and Cyclophosphamide [J] . Krais John J., Virani Needa, McKernan Patrick H., Molecular cancer therapeutics . 2017,第9期

机译：抗肿瘤协同作用和增强的存活与肿瘤脉管系统靶向酶前药系统，雷帕霉素和环磷酰胺
2. Antitumor activity of an enzyme prodrug therapy targeted to the breast tumor vasculature [J] . VanRiteB.D., KraisJ.J., CherryM., Cancer investigation . 2013,第1a10期

机译：针对乳腺肿瘤脉管系统的酶前药疗法的抗肿瘤活性
3. Prodrugs for nitroreductase-based cancer therapy-3: Antitumor activity of the novel dinitroaniline prodrugs/Ssap-NtrB enzyme suicide gene system: Synthesis, in vitro and in silico evaluation in prostate cancer [J] . Tokay Esra, Gungor Tugba, Hacioglu Nelin, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2020,第期

机译：基于硝化酶的癌症治疗前药-3：新型Dinitroaniline前药/ SSAP-NTRB酶自杀基因系统的抗肿瘤活性：合成，体外和硅藻癌中的硅评价
4. Targeted Enzyme/Prodrug Therapy for the Treatment of Solid Tumors [C] . Brent D. Van Rite, Roger G. Harrison Annual biochemical engineering symposium . 2012

机译：靶向酶/前药治疗实体瘤的治疗
5. Oncolytic adenoviruses in combination treatments for cancer: Examining the roles of cyclophosphamide and radiation in enhancing antitumor efficacy and viral replication and biodistribution in the Syrian hamster. [D] . Young, Brittany A. 2013

机译：溶瘤腺病毒在癌症联合治疗中的作用：研究环磷酰胺和放射线在增强叙利亚仓鼠的抗肿瘤功效以及病毒复制和生物分布方面的作用。
6. Tumor Vasculature-Targeted Recombinant Mutated Human TNF-α Enhanced the Antitumor Activity of Doxorubicin by Increasing Tumor Vessel Permeability in Mouse Xenograft Models [O] . Changli Jiang, Junzhou Niu, Meng Li, -1

机译：通过增加小鼠异种移植模型中的肿瘤血管渗透性靶向肿瘤血管的重组突变人TNF-α增强了阿霉素的抗肿瘤活性。
7. Tumor vasculature-targeted recombinant mutated human TNF-α enhanced the antitumor activity of doxorubicin by increasing tumor vessel permeability in mouse xenograft models. [O] . Changli Jiang, Junzhou Niu, Meng Li, 2014

机译：肿瘤脉管系统靶向的重组突变的人TNF-α通过增加小鼠异种移植模型中的肿瘤血管通透性来增强阿霉素的抗肿瘤活性。

Antitumor Synergism and Enhanced Survival with a Tumor Vasculature–Targeted Enzyme Prodrug System, Rapamycin, and Cyclophosphamide

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