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Structural investigation of the interaction between Combretastatin A-4 analogues with benzoxazolone scaffold and αβ-tubulin

机译：苯并恶唑酮支架和αβ-小蛋白组合甘蔗苷素A-4类似物相互作用的结构研究

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Rusi Rusev; Mariana Gerova; Georgi Atanasov; Desislava Stanisheva; Hristina Sbirkova-Dimitrova; Margarita Apostolova; Ognyan Petrov; Boris Shivachev;
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1. Combretastatin A-4 analogues with benzoxazolone scaffold: Synthesis, structure and biological activity [J] . Gerova Mariana S., Stateva Silviya R., Radonova Elena M., European Journal of Medicinal Chemistry: Chimie Therapeutique . 2016,第Null期

机译：Combretastatin A-4类似物与苯并恶唑酮骨架的合成，结构和生物学活性
2. Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors [J] . Romagnoli Romeo, Oliva Paola, Kimatrai Salvador Maria, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2019,第期

机译：新型邻近二芳基替代1H-吡唑基类似物的设计，合成及生物学评价A-4作为高效微管蛋白聚合抑制剂
3. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β -lactam bridged combretastatin A-4 analogues as potent antitumor agents [J] . Pengfei Zhou, Yuru Liang, Hao Zhang, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2018,第期

机译：手性β-Lactam桥上桥上的桥蛋白的设计，合成，生物学评价和共晶结构作为有效抗肿瘤剂的α-4类似物
4. QSAR and Molecular Docking Study of a Series of Combretastatin Analogues Tubulin Inhibitors [C] . Yubin Ji, Ran Tian, Wenhan Lin International Conference on Life System Modeling and Simulation(LSMS 2007); 20070914-17; Shanghai(CN) . 2007

机译：QSAR和一系列Combretastatin类似物微管蛋白抑制剂的分子对接研究
5. Structure-activity relationships and thermodynamics of combretastatin A-4 and A-1 derivatives as potential inhibitors of tubulin polymerization. [D] . Mugabe, Benon E. 2006

机译：康布雷他汀A-4和A-1衍生物作为微管蛋白聚合的潜在抑制剂的结构活性关系和热力学。
6. Synthesis of Combretastatin A-4 and 3′-Aminocombretastatin A-4 derivatives with Aminoacid Containing Pendants and Study of their Interaction with Tubulin and as Downregulators of the VEGF hTERT and c-Myc Gene Expression [O] . Raül Agut, Eva Falomir, Juan Murga, 2020

机译：含氨基酸侧链的Combretastatin A-4和3-Aminocombretastatin A-4衍生物的合成及其与微管蛋白的相互作用以及作为VEGFhTERT和c-Myc基因表达下调剂的相互作用的研究
7. Molecular modeling study, synthesis and biological evaluation of combretastatin A-4 analogues as anticancer agents and tubulin inhibitors [O] . Yang Ping Quan, Li Ping Cheng, Tian Chi Wang, 2018

机译：Combretastatin A-4类似物作为抗癌剂和微管蛋白抑制剂的分子建模研究，合成和生物学评价

Structural investigation of the interaction between Combretastatin A-4 analogues with benzoxazolone scaffold and αβ-tubulin

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