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Intrathecal Injection of the ς1Receptor Antagonist BD1047 Blocks Both Mechanical Allodynia and Increases in Spinal NR1 Expression during the Induction Phase of Rodent Neuropathic Pain

机译：intr1receptor拮抗剂BD1047的鞘内注射患者阻断机械异常疼痛，并在啮齿动物神经性疼痛的诱导阶段期间脊髓NR1表达增加

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Dae-Hyun Roh; Hyun-Woo Kim; Seo-Yeon Yoon; Hyoung-Sig Seo; Young-Bae Kwon; Kee-Won Kim; Ho-Jae Han; Alvin J. Beitz; Heung-Sik Na; Jang-Hern Lee;
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1. Intrathecal injection of the sigma(1) receptor antagonist BD1047 blocks both mechanical allodynia and increases in spinal NR1 expression during the induction phase of rodent neuropathic pain. [J] . Roh DH, Kim HW, Yoon SY, Anesthesiology . 2008,第5期

机译：鞘内注射sigma（1）受体拮抗剂BD1047既可以阻止机械性异常性疼痛，又可以在啮齿动物神经性疼痛的诱导阶段增加脊髓NR1的表达。
2. Sigma-1 Receptor Antagonist BD1047 Reduces Mechanical Allodynia in a Rat Model of Bone Cancer Pain through the Inhibition of Spinal NR1 Phosphorylation and Microglia Activation [J] . ShanshanZhu, ChenchenWang, YuanHan, Mediators of inflammation . 2015,第6期

机译：Sigma-1受体拮抗剂BD1047通过抑制脊髓NR1磷酸化和小胶质细胞活化来降低骨癌痛大鼠模型的机械性异常性疼痛。
3. Sigma-1 Receptor Antagonist BD1047 Reduces Mechanical Allodynia in a Rat Model of Bone Cancer Pain through the Inhibition of Spinal NR1 Phosphorylation and Microglia Activation [J] . Zhu Shanshan, Wang Chenchen, Han Yuan, Mediators of inflammation . 2015,第8期

机译：Sigma-1受体拮抗剂BD1047通过抑制脊髓NR1磷酸化和微胶质激活，减少了骨癌疼痛大鼠模型中的机械异常性疼痛
4. Aging confers an increase in sensitivity and sensitization to pain and results in shifts of spinal NR1 expression [D] . Jenschke, Monica 2009

机译：衰老可增加对疼痛的敏感性和敏感性，并导致脊髓NR1表达的改变
5. Sigma-1 Receptor Antagonist BD1047 Reduces Mechanical Allodynia in a Rat Model of Bone Cancer Pain through the Inhibition of Spinal NR1 Phosphorylation and Microglia Activation [O] . Shanshan Zhu, Chenchen Wang, Yuan Han, 2015

机译：Sigma-1受体拮抗剂BD1047通过抑制脊髓NR1磷酸化和小胶质细胞活化来降低骨癌痛大鼠模型的机械性异常性疼痛。
6. Sigma-1 Receptor Antagonist BD1047 Reduces Mechanical Allodynia in a Rat Model of Bone Cancer Pain through the Inhibition of Spinal NR1 Phosphorylation and Microglia Activation [O] . Shanshan Zhu, Chenchen Wang, Yuan Han, 2015

机译：Sigma-1受体拮抗剂BD1047通过抑制脊髓NR1磷酸化和微胶质激活来减少骨癌疼痛大鼠疼痛的机械异常性疼痛

Intrathecal Injection of the ς1Receptor Antagonist BD1047 Blocks Both Mechanical Allodynia and Increases in Spinal NR1 Expression during the Induction Phase of Rodent Neuropathic Pain

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