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Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease

机译：建立管道以发现和验证新的治疗靶点和用于阿尔茨海默病的铅化合物

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David A. Bennett; Lei Yu; Philip L. De Jager;
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1. Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease [J] . BennettD.A., YuL., DeJagerP.L. Biochemical Pharmacology . 2014,第4期

机译：建立管道以发现和验证阿尔茨海默氏病的新型治疗靶标和先导化合物
2. Validation of the Neuroinflammation Cycle as a Drug Discovery Target Using Integrative Chemical Biology and Lead Compound Development with an Alzheimer's Disease-Related Mouse Model [J] . Wenhui Hu Hantamalala Ralay Ranaivo Jeffrey M. Craft Linda J. Van Eldik D. Martin Watterson Current Alzheimer Research . 2005,第2期

机译：使用综合化学生物学和与阿尔茨海默氏病相关的小鼠模型开发的先导化合物，验证神经炎症周期作为药物发现的靶标
3. A Systematic Strategy for Discovering a Therapeutic Drug for Alzheimer’s Disease and Its Target Molecule [J] . Zhiyou Yang, Tomoharu Kuboyama, Chihiro Tohda Frontiers in Pharmacology . 2017,第2016期

机译：寻找阿尔茨海默氏病及其靶分子治疗药物的系统策略
4. Lead structures for active immunisation against Alzheimer's disease (AD) upon eluciation of a plaque-specific epitope recognised by therapeutically active antisera from transgenic AD mice [C] . M.Przybylski, J.McLaurin, R.E.Cecal, European Peptide Symposium . 2002

机译：用于从转基因广告小鼠那里通过治疗活性抗血清识别的斑块特异性表位时对阿尔茨海默病（AD）进行主动免疫的铅结构
5. Integration of Alzheimer's Disease Genetics, Myeloid Cell Genomics and Gene Regulatory Networks Reveals Novel Disease Mechanisms, Drug Targets and Candidate Therapeutics [D] . Novikova, Gloriia. 2021

机译：阿尔茨海默病遗传学，骨髓细胞基因组学和基因监管网络的整合揭示了新型疾病机制，药物目标和候选治疗方法
6. Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimers disease [O] . David A. Bennett, Lei Yu, Philip L. De Jager -1

机译：建立管道以发现和验证阿尔茨海默氏病的新型治疗靶标和先导化合物
7. Discovering Biomarkers and Pathways Shared by Alzheimer’s Disease and Ischemic Stroke to Identify Novel Therapeutic Targets [O] . Md. Rezanur Rahman, Tania Islam, Md. Shahjaman, 2019

机译：发现Alzheimer疾病和缺血性卒中共享的生物标志物和途径，以识别新的治疗目标
8. Using High Throughput Screens to Identify Lead Compounds for Alzheimer's Disease Therapeutics [R] . Chen, J. 2008

机译：使用高通量筛选鉴定阿尔茨海默病治疗的先导化合物

Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease

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