首页> 外文OA文献 >Mutations in the genes for hepatocyte nuclear factor (HNF)-1alpha, -4alpha, -1beta, and -3beta; the dimerization cofactor of HNF-1; and insulin promoter factor 1 are not common causes of early-onset type 2 diabetes in Pima Indians

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Mutations in the genes for hepatocyte nuclear factor (HNF)-1alpha, -4alpha, -1beta, and -3beta; the dimerization cofactor of HNF-1; and insulin promoter factor 1 are not common causes of early-onset type 2 diabetes in Pima Indians

机译：肝细胞核因子（HNF）-1Alpha，-4Alpha，-1beta和-3beta的基因中的突变; HNF-1的二聚辅助弧剂;胰岛素启动子因子1不是PIMA印第安人早期出现2型糖尿病的常见原因

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L. J. Baier; P. A. Permana; M. Traurig; A. Dobberfuhl; C. Wiedrich; J. Sutherland; P. Thuillez; G. Luczy-Bachman; M. Hara; Y. Horikawa; Y. Hinokio; R. L. Hanson; C. Bogardus;
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1. Mutations in the genes for hepatocyte nuclear factor (HNF)-1alpha, -4alpha, -1beta, and -3beta; the dimerization cofactor of HNF-1; and insulin promoter factor 1 are not common causes of early-onset type 2 diabetes in Pima Indians. [J] . Baier LJ, Permana PA, Traurig M, Diabetes care . 2000,第3期

机译：肝细胞核因子（HNF）-1alpha，-4alpha，-1beta和-3beta基因突变; HNF-1的二聚化辅因子;在皮马印第安人中，胰岛素和促胰岛素因子1不是2型糖尿病早期发作的常见原因。
2. Studies of the variability of the hepatocyte nuclear factor-1beta (HNF-1beta / TCF2) and the dimerization cofactor of HNF-1 (DcoH / PCBD) genes in relation to type 2 diabetes mellitus and beta-cell function. [J] . Ek J, Grarup N, Urhammer SA, Human mutation . 2001,第4期

机译：研究肝细胞核因子-1β（HNF-1beta / TCF2）和HNF-1（DcoH / PCBD）基因的二聚化辅因子与2型糖尿病和β细胞功能有关的变异性。
3. Mutations in hepatocyte nuclear factor 4alpha (HNF4alpha) gene associated with diabetes result in greater loss of HNF4alpha function in pancreatic beta-cells than in nonpancreatic beta-cells and in reduced activation of the apolipoprotein CIII promot [J] . Oxombre B, Moerman E, Eeckhoute J, Journal of molecular medicine: Official organ of the "Gesellschaft Deutscher Naturforscher und Arzte." . 2002,第7期

机译：与糖尿病相关的肝细胞核因子4alpha（HNF4alpha）基因突变导致胰腺β细胞中的HNF4alpha功能丧失比非胰腺β细胞中更大，并且载脂蛋白CIII促进剂的激活减少
4. Determinants of cofactor recruitment and transcriptional activity for hepatocyte nuclear factor 4alpha (HNF4alpha). [D] . Ruse, Michael Dean, Jr. 2002

机译：肝细胞核因子4α（HNF4alpha）的辅助因子募集和转录活性的决定因素。
5. Berry Phenolic Compounds Increase Expression of Hepatocyte Nuclear Factor-1α (HNF-1α) in Caco-2 and Normal Colon Cells Due to High Affinities with Transcription and Dimerization Domains of HNF-1α [O] . Luis M. Real Hernandez, Junfeng Fan, Michelle H. Johnson, -1

机译：浆果酚类化合物由于具有亲和力的HNF-1α转录和二聚结构域而增加了Caco-2和正常结肠细胞中肝细胞核因子1α（HNF-1α）的表达。
6. Promoter-Specific Repression of Hepatocyte Nuclear Factor (HNF)-1β and HNF-1α Transcriptional Activity by an HNF-1β Missense Mutant Associated with Type 5 Maturity-Onset Diabetes of the Young with Hepatic and Biliary Manifestations [O] . Sachiko Kitanaka, Yuko Miki, Yasuhide Hayashi, 2004

机译：通过HNF-1β致畸突变体对肝细胞核因子（HNF）-1β和HNF-1α转录活性的启动子特异性抑制与肝癌和胆道表现出的5型成熟型糖尿病相关

Mutations in the genes for hepatocyte nuclear factor (HNF)-1alpha, -4alpha, -1beta, and -3beta; the dimerization cofactor of HNF-1; and insulin promoter factor 1 are not common causes of early-onset type 2 diabetes in Pima Indians

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