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Mechanistic and Quantitative Understanding of Pharmacokinetics in Zebrafish Larvae through Nanoscale Blood Sampling and Metabolite Modeling of Paracetamol

机译：通过纳米级血液取样和扑热氨基醇代谢素模拟斑马鱼幼虫药代动力学的机械和定量理解

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Rob C. Van Wijk; Elke H.J. Krekels; Vasudev Kantae; Anita Ordas; Thijs Kreling; Amy C. Harms; Thomas Hankemeier; Herman P. Spaink; Piet H. van der Graaf;
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1. Mechanistic and Quantitative Understanding of Pharmacokinetics in Zebrafish Larvae through Nanoscale Blood Sampling and Metabolite Modeling of Paracetamol [J] . Van Wijk Rob C., Krekels Elke H. J., Kantae Vasudev, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2019,第1期

机译：通过纳米级血液取样和扑热氨基醇代谢素模拟斑马鱼幼虫药代动力学的机械和定量理解
2. Pharmacokinetic Modeling of Paracetamol Uptake and Clearance in Zebrafish Larvae: Expanding the Allometric Scale in Vertebrates with Five Orders of Magnitude [J] . Zebrafish . 2016,第6期

机译：斑马鱼幼虫中扑热息痛摄取和清除的药代动力学模型：扩大脊椎动物的异速代谢规模，幅度为五个数量级。
3. Impact of post-hatching maturation on the pharmacokinetics of paracetamol in zebrafish larvae [J] . Rob C. van Wijk, Elke H. J. Krekels, Vasudev Kantae, Scientific reports. . 2019,第1期

机译：孵化后成熟对斑马鱼幼虫中扑热息痛药代动力学的影响
4. High Resolution Accurate Mass MS and MS/MS for Simultaneous Quantitative and Qualitative Analysis in Complex Biological Samples: Pharmacokinetics Analysis and Metabolite Identification of Clozapine [C] . Na Pi, Shane E. Tichy, Adam Amaral, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

机译：高分辨率精确的质量MS和MS / MS，用于复杂生物样品中同时定量和定性分析：药代动力学分析和氯氮平的代谢物鉴定
5. Population pharmacokinetics of intravenous acetaminophen (paracetamol) and its metabolites in neonates. [D] . Cook, Sarah Fogley. 2015

机译：新生儿对乙酰氨基酚（扑热息痛）及其代谢产物的群体药代动力学。
6. Pharmacokinetic Modeling of Paracetamol Uptake and Clearance in Zebrafish Larvae: Expanding the Allometric Scale in Vertebrates with Five Orders of Magnitude [O] . Vasudev Kantae, Elke H.J. Krekels, Anita Ordas, -1

机译：扑热息痛在斑马鱼幼虫中的摄取和清除的药代动力学模型：以五个数量级扩大脊椎动物的异速异度尺度。
7. Quantitative and Mechanistic Understanding of AZD1775 Penetration across Human Blood–Brain Barrier in Glioblastoma Patients Using an IVIVE–PBPK Modeling Approach [O] . Jing Li, Jianmei Wu, Xun Bao, 2017

机译：使用IVIVE-PBPK建模方法对胶质母母血管瘤患者人血脑屏障渗透的定量和机械理解

Mechanistic and Quantitative Understanding of Pharmacokinetics in Zebrafish Larvae through Nanoscale Blood Sampling and Metabolite Modeling of Paracetamol

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