The effect of Saqez (Pistacia atlantica) ointment on the treatment of nipple fissure and nipple pain in breastfeeding women

摘要

Background: Nipple fissure is a common problem in breastfeeding women, and the main reason for the earlydiscontinuation of breastfeeding.Objective: To determine the effect of Saqez (Pistacia atlantica) ointment on the treatment of nipple fissure andnipple pain in breastfeeding women.Methods: This randomized clinical trial was conducted on 100 subjects admitted to the health centers in Tehran,Iran from mid-July to mid-November 2015. The subjects were randomly divided into two equal groups of 50 forthe Saqez ointment group and the control group. The subjects were divided into the two groups through randomallocation in Excel. The subjects were monitored on day 1, 3 and 7. Data were analyzed in SAS using theCumulative Logit model and in SPSS-21 using Mann-Whitney, independent-samples t-test, the Chi square andFisher's exact test.Results: No significant differences were observed between the two groups in terms of their demographic andfertility characteristics. The Cumulative Logit model showed that high levels of nipple fissure and pain weresignificantly less frequent in the Saqez group compared to the control group (p<0.001). There was about 83%reduction in the severity of fissure and 85 %in the severity of pain in the Saqez group compared to the controlgroup (p<0.001).Conclusion: Saqez ointment is more effective in the treatment of nipple fissures and pain than breast milk. Asthis study was done for the first time, judgment about the conclusive efficacy of Saqez ointment on the nipplefissure, needs further similar studies.Trial registration: The trial was registered at the Iranian Registry of Clinical Trials (http://www.irct.ir) with theIrct ID: IRCT2015080723535N1.Funding: The authors received no financial support for the research, authorship, and/or publication of this article