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Structure-guided design of antibacterials that allosterically inhibit DNA gyrase

机译：构成抑制DNA乙酶的抗菌剂的结构导向设计

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Reema K. Thalji; Kaushik Raha; Daniele Andreotti; Anna Checchia; Haifeng Cui; Giovanni Meneghelli; Roberto Profeta; Federica Tonelli; Simona Tommasi; Tania Bakshi; Brian T. Donovan; Alison Howells; Shruti Jain; Christopher Nixon; Geoffrey Quinque; Lynn McCloskey; Benjamin D. Bax; Margarete Neu; Pan F. Chan; Robert A. Stavenger;
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1. Structure-guided design of antibacterials that allosterically inhibit DNA gyrase [J] . Thalji Reema K., Raha Kaushik, Andreotti Daniele, Bioorganic and Medicinal Chemistry Letters . 2019,第11期

机译：构成抑制DNA乙酶的抗菌剂的结构导向设计
2. Novel dual-targeting benzimidazole urea inhibitors of DNA gyrase and topoisomerase IV possessing potent antibacterial activity: Intelligent design and evolution through the judicious use of structure-guided design and stucture-activity relationships [J] . Charifson PS, Grillot AL, Grossman TH, Journal of Medicinal Chemistry . 2008,第17期

机译：具有强力抗菌活性的新型DNA促旋酶和拓扑异构酶IV双靶标苯并咪唑脲抑制剂：通过明智地使用结构指导的设计和结构与活性的关系，智能设计和开发
3. Design, synthesis and antibacterial properties of pyrimido[4,5- b ]indol-8-amine inhibitors of DNA gyrase [J] . David H. McGarry, Ian R. Cooper, Rolf Walker, Bioorganic and Medicinal Chemistry Letters . 2018,第17期

机译：嘧啶的设计，合成和抗菌性能[4,5- b]吲哚-8-胺抑制剂DNA乙酶
4. Antibacterial design based on the structures of gyrase-inhibitor complexes [C] . Richard Pauptit, Simon Weston, Alex Breeze, NATO advanced study institute on experimental and computational approaches to structure-based drug design . 1998

机译：基于乙酶抑制剂络合物结构的抗菌设计
5. Computer-Aided Identification of New DNA Gyrase Inhibitors with Activity against Staphylococcus aureus. [D] . Werner, Malela Mwamufiya. 2014

机译：具有金黄色葡萄球菌活性的新型DNA促旋酶抑制剂的计算机辅助鉴定。
6. Design Synthesis and Antibacterial Screening of Some Novel Heteroaryl-Based Ciprofloxacin Derivatives as DNA Gyrase and Topoisomerase IV Inhibitors [O] . Lamya H. Al-Wahaibi, Amer A. Amer, Adel A. Marzouk, 2021

机译：一种新型杂芳基环戊氧氟沙星衍生物的设计合成和抗菌筛选作为DNA腺苷酸和拓扑异构酶IV抑制剂
7. Thiophene antibacterials that allosterically stabilize DNA-cleavage complexes with DNA gyrase [O] . Chan, PF, Germe, T, Bax, BD, 2017

机译：噻吩类抗菌剂，可通过DNA促旋酶变构稳定DNA裂解复合物

Structure-guided design of antibacterials that allosterically inhibit DNA gyrase

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