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Antitumor activity without on-target off-tumor toxicity of GD2–chimeric antigen receptor T cells in patients with neuroblastoma

机译：没有针对神经母细胞瘤患者的GD2-嵌合抗原受体T细胞的抗肿瘤活性没有靶向靶向肿瘤毒性

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Karin Straathof; Barry Flutter; Rebecca Wallace; Neha Jain; Thalia Loka; Sarita Depani; Gary Wright; Simon Thomas; Gordon Weng-Kit Cheung; Talia Gileadi; Sian Stafford; Evangelia Kokalaki; Jack Barton; Clare Marriott; Dyanne Rampling; Olumide Ogunbiyi; Ayse U. Akarca; Teresa Marafioti; Sarah Inglott; Kimberly Gilmour; Muhammad Al-Hajj; William Day; Kieran McHugh; Lorenzo Biassoni; Natalie Sizer; Claire Barton; David Edwards; Ilaria Dragoni; Julie Silvester; Karen Dyer; Stephanie Traub; Lily Elson; Sue Brook; Nigel Westwood; Lesley Robson; Ami Bedi; Karen Howe; Ailish Barry; Catriona Duncan; Giuseppe Barone; Martin Pule; John Anderson;
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1. Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma. [J] . Louis CU, Savoldo B, Dotti G, Blood: The Journal of the American Society of Hematology . 2011,第23期

机译：神经母细胞瘤患者嵌合抗原受体阳性T细胞的抗肿瘤活性和长期命运。
2. Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma. [J] . Louis CU, Savoldo B, Dotti G, Blood: The Journal of the American Society of Hematology . 2011,第23期

机译：神经母细胞瘤患者嵌合抗原受体阳性T细胞的抗肿瘤活性和长期命运。
3. Therapeutic Potential of T Cell Chimeric Antigen Receptors (CARs) in Cancer Treatment: Counteracting Off-Tumor Toxicities for Safe CAR T Cell Therapy [J] . Gross Gideon, Eshhar Zelig Annual Review of Pharmacology and Toxicology . 2016,第Null期

机译：T细胞嵌合抗原受体（CARs）在癌症治疗中的治疗潜力：抵消肿瘤的毒性，以安全地进行CAR T细胞治疗
4. CHIMERIC ANTIGEN RECEPTORS FOR THE TREATMENT OF CANINE B CELL MALIGNANCIES [C] . Heather Wilson-Robles Conference of the American College of Veterinary Internal Medicine . 2014

机译：用于治疗犬B细胞恶性肿瘤的嵌合抗原受体
5. Targeting the Disialoganglioside GD2 with Chimeric Antigen Receptor T Cells for Immunotherapy in Diffuse Midline Gliomas, and Exploration of Neuron-OPC Synaptic Connectivity in the Context of Adaptive Myelination [D] . Mount, Christopher W. 2020

机译：用嵌合抗原受体T细胞靶向Diaialoganglioside GD2，用于在弥漫性中线胶质瘤中的免疫疗法，以及在适应性髓鞘中的背景下探索神经元-Popaptic连通性
6. The inducible caspase-9 suicide gene system as a safety switch to limit on-target off-tumor toxicities of chimeric antigen receptor T cells [O] . Tessa Gargett, Michael P. Brown 2014

机译：可诱导的caspase-9自杀基因系统作为安全开关以限制嵌合抗原受体T细胞的靶向非肿瘤毒性
7. The inducible caspase-9 suicide gene system as a ‘safety switch’ to limit on-target, off-tumor toxicities of chimeric antigen receptor T-cells. [O] . Tessa eGargett, Michael eBrown 2014

机译：可诱导的caspase-9自杀基因系统作为“安全开关”来限制嵌合抗原受体T细胞的靶向，非肿瘤毒性。

Antitumor activity without on-target off-tumor toxicity of GD2–chimeric antigen receptor T cells in patients with neuroblastoma

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