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Altering the Substrate Specificity of Acetyl-CoA Synthetase by Rational Mutagenesis of the Carboxylate Binding Pocket

机译：通过羧酸盐结合口袋的合理诱变改变乙酰-CoA合成酶的底物特异性

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Naazneen Sofeo; Jason H. Hart; Brandon Butler; David J. Oliver; Marna D. Yandeau-Nelson; Basil J. Nikolau;
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年度 2019
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1. Altering the Substrate Specificity of Acetyl-CoA Synthetase by Rational Mutagenesis of the Carboxylate Binding Pocket [J] . Sofeo Naazneen, Hart Jason H., Butler Brandon, ACS Synthetic Biology . 2019,第6期

机译：通过合理诱变羧酸盐结合口袋改变乙酰-CoA合成酶的底物特异性
2. Characterization of the Acyl Substrate Binding Pocket of Acetyl-CoA Synthetase [J] . Cheryl Ingram-Smith, Barrett I.Woods, Kerry S.Smith Biochemistry . 2006,第38期

机译：乙酰辅酶A合成酶的酰基底物结合口袋的表征
3. Expanding Substrate Specificity of omega-Transaminase by Rational Remodeling of a Large Substrate-Binding Pocket [J] . Han Sang-Woo, Park Eul-Soo, Dong Joo-Young, Advanced synthesis & catalysis . 2015,第12期

机译：通过对大型底物结合口袋的合理改造来扩大ω-转氨酶的底物特异性
4. Species-Specific Differences in the Operational RNA Code for Aminoacylation of tRNATrp and Selection of Bacillus Subtilis Tryptophanyl-tRNA Synthetase Binding Aptamers [C] . 19th tRNA workshop tRNA 2002"" . 2002

机译：种特定差异的操作RNA编码的tRNATrp的氨基酰化和枯草芽孢杆菌色氨酸-tRNA合成酶结合适体的选择。
5. Altering the substrate specificity of 2-keto-3-deoxy-6-phosphogluconate aldolase by rational mutagenesis and directed evolution [D] . Cheriyan, Manoj 2007

机译：通过合理的诱变和定向进化改变2-酮-3-脱氧-6-磷酸葡萄糖醛酸醛缩酶的底物特异性
6. AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity [O] . Jessica M. A. Blair, Vassiliy N. Bavro, Vito Ricci, 2015

机译：AcrB结合药物的口袋替代赋予临床相关耐药性并改变了底物特异性
7. AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity [O] . Blair, Jessica M. A., Bavro, Vassiliy N., Vito, Ricci, 2015

机译：AcrB结合药物的口袋替代赋予临床相关耐药性并改变了底物特异性

Altering the Substrate Specificity of Acetyl-CoA Synthetase by Rational Mutagenesis of the Carboxylate Binding Pocket

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