首页> 外文OA文献 >Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor

【2h】

Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor

机译：JNJ-42756493（Erdafitinib）的发现和药理学表征，一种功能选择性小分子FGFR家族抑制剂

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

著录项
引文网络
相似文献
相关主题

著录项

作者
Timothy P.S. Perera; Eleonora Jovcheva; Laurence Mevellec; Jorge Vialard; Desiree De Lange; Tinne Verhulst; Caroline Paulussen; Kelly Van De Ven; Peter King; Eddy Freyne; David C. Rees; Matthew Squires; Gordon Saxty; Martin Page; Christopher W. Murray; Ron Gilissen; George Ward; Neil T. Thompson; David R. Newell; Na Cheng; Liang Xie; Jennifer Yang; Suso J. Platero; Jayaprakash D. Karkera; Christopher Moy; Patrick Angibaud; Sylvie Laquerre; Matthew V. Lorenzi;
展开▼
作者单位

展开▼
年度 2017
总页数
原文格式 PDF
正文语种
中图分类

相似文献

外文文献
中文文献
专利

1. Oncogenic Characterization and Pharmacologic Sensitivity of Activating Fibroblast Growth Factor Receptor (FGFR) Genetic Alterations to the Selective FGFR Inhibitor Erdafitinib [J] . Karkera Jayaprakash D., Cardona Gabriela Martinez, Bell Katherine, Molecular cancer therapeutics . 2017,第8期

机译：活化成纤维细胞生长因子受体（FGFR）遗传改变对选择性FGFR抑制剂Erdafitinib的致力学表征及药理敏感性
2. A successful collaboration between academia, biotech and pharma led to discovery of erdafitinib, a selective FGFR inhibitor recently approved by the FDA [J] . Christopher W. Murray, David R. Newell, Patrick Angibaud MedChemComm . 2019,第9期

机译：学术界，生物科技和制药之间的成功合作导致了Erdafitinib的发现，这是最近被FDA批准的选择性FGFR抑制因素
3. Characterization of BMS-911543, a functionally selective small-molecule inhibitor of JAK2 [J] . A V Purandare, T M McDevitt, H Wan, Leukemia . 2012,第2期

机译：BMS-911543，JAK2的功能选择性小分子抑制剂的表征
4. Design, synthesis, and activity evaluation of broad-spectrum small-molecule inhibitors of anti-apoptofic Bcl-2 family proteins: Characteristics of broad-spectrum protein binding and its effects on anti-tumor activity [C] . Can-Hui Zheng, Jia-Guo Lv, Ju Zhu, International conference of molecular simulations and applied informatics technologies . 2012

机译：抗凋亡Bcl-2家族蛋白的广谱小分子抑制剂的设计，合成和活性评估：广谱蛋白结合的特征及其对抗肿瘤活性的影响
5. Pharmacological Characterization of TAS05567, a Potent and Selective Inhibitor of Spleen Tyrosine Kinase, in Animal Models of Inflammatory Diseases and B-cell Malignancies [D] . 林宏明 2019

机译：TAS05567，脾酪氨酸激酶的强效和选择性抑制剂，在炎症性疾病和B细胞恶性动物模型中的药理特性
6. Selective inhibition of the Kir2 family of inward rectifier potassium channels by a small molecule probe: the discovery SAR and pharmacological characterization of ML133 [O] . Hao-Ran Wang, Meng Wu, Haibo Yu, -1

机译：通过小分子探针选择性抑制KIR2内陆整流钾通道的选择：ML133的发现SAR和药理表征
7. Oncogenic Characterization and Pharmacologic Sensitivity of Activating Fibroblast Growth Factor Receptor (FGFR) Genetic Alterations to the Selective FGFR Inhibitor Erdafitinib [O] . Jayaprakash D. Karkera, Gabriela Martinez Cardona, Katherine Bell, 2017

机译：激活成纤维细胞生长因子受体（FGFR）遗传改变对选择性FGFR抑制剂Erdafitinib的致力学表征和药理学敏感性

Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor

著录项

引文网络

相似文献

相关主题

期刊订阅