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Factors Affecting Pregnancy Rate Following Fallopian Tube Recanalization in Women with Proximal Fallopian Tube Obstruction

机译:近端输卵管梗阻妇女输卵管重新化后影响妊娠率的因素

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摘要

Fallopian tube obstruction is a major cause of female infertility. We aimed to evaluate the factors potentially affecting pregnancy rate following fallopian tube recanalization (FTR) in infertile women with proximal fallopian tube obstruction. Data was retrospectively collected for 61 women (25, primary infertility; 36, secondary infertility) who underwent FTR at our institution. Bivariable and multivariable analyses of clinical pregnancy rates in relation to the following factors were performed: primary vs. secondary infertility, duration of infertility, age at the time of FTR, unilateral vs. bilateral obstruction, and previous pelvic interventions. All women who underwent fluoroscopically guided transcervical FTR of one or both proximally obstructed tubes were successfully recanalized (technical success rate, 100%). Within a year after FTR, 41% of women had conceived. None of the studied variables was significantly associated with pregnancy rate on bivariable analysis. Nevertheless, on multivariable analysis, the type and duration of infertility were significantly associated with pregnancy among women aged <35 years at the time of FTR. Our findings regarding pregnancy rates following FTR reflect the diversity of the patient population and suggest the presence of multiple contributing factors. Younger women with secondary infertility for <5 years are highly likely to achieve conception following FTR.
机译:输卵管梗阻是女性不孕症的主要原因。我们旨在评估近端输卵管梗阻不育妇女输卵管重新化(FTR)潜在影响妊娠率的因素。回顾性地收集了61名女性(25名,主要不育症; 36,二次不孕)在我们的机构接受了审查的数据。对临床妊娠率的可行和多变量分析是关于以下因素的临床妊娠率:初级与二次不孕,不孕症的持续时间,FTR时的年龄,单侧与双侧梗阻以及以前的盆腔干预。所有接受透视引导的跨障型近似阻塞管的透视脊椎诊断FTR的所有妇女都已成功重新定义(技术成功率,100%)。在FTR之后一年内,41%的女性设想了。没有研究的变量与可生物分析的妊娠率显着相关。然而,在多变量分析中,不孕症的类型和持续时间与FTR时患者的女性妊娠显着相关。我们对FTR后怀孕率的调查结果反映了患者人口的多样性,并建议存在多种贡献因素。具有次级不孕症<5年的年轻女性很可能在FTR之后实现概念。

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