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SB-649915-B, a Novel 5-HT1A/B Autoreceptor Antagonist and Serotonin Reuptake Inhibitor, is Anxiolytic and Displays Fast Onset Activity in the Rat High Light Social Interaction Test

机译：SB-649915-B，一种新的5-HT1A / B吸尘器拮抗剂和血清素再摄取抑制剂，是抗焦虑的，在大鼠高光社交测试中显示出快速发作活动

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Kathryn R Starr; Gary W Price; Jeannette M Watson; Peter J Atkinson; Roberto Arban; Sergio Melotto; Lee A Dawson; Jim J Hagan; Neil Upton; Mark S Duxon;
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1. SB-649915-B, a Novel 5-HT1A|[sol]|B Autoreceptor Antagonist and Serotonin Reuptake Inhibitor, is Anxiolytic and Displays Fast Onset Activity in the Rat High Light Social Interaction Test [J] . Kathryn R Starr, Gary W Price, Jeannette M Watson, Neuropsychopharmacology . 2007,第10期

机译：SB-649915-B是一种新型5-HT1A | [sol] | B自体拮抗剂和5-羟色胺再摄取抑制剂，具有抗焦虑作用，并在大鼠强光社交互动测试中显示出快速起效的作用。
2. Characterization of the potent 5-HT(1A/B) receptor antagonist and serotonin reuptake inhibitor SB-649915: preclinical evidence for hastened onset of antidepressant/anxiolytic efficacy. [J] . Watson JM, Dawson LA CNS drug reviews . 2007,第2期

机译：有效的5-HT（1A / B）受体拮抗剂和5-羟色胺再摄取抑制剂SB-649915的表征：加速抗抑郁/抗焦虑药效的临床前证据。
3. Simultaneous blockade of 5-HT1A/B receptors and 5-HT transporters results in acute increases in extracellular 5-HT in both rats and guinea pigs: in vivo characterization of the novel 5-HT1A/B receptor antagonist/5-HT transport inhibitor SB-649915-B [J] . Zoë A. Hughes, Kathryn R. Starr, Claire M. Scott, Psychopharmacology . 2007,第1期

机译：5-HT1A / B 受体和5-HT转运蛋白的同时封锁导致大鼠和豚鼠细胞外5-HT急性增加：新型5-HT1A / B 受体的体内特征拮抗剂/ 5-HT运输抑制剂SB-649915-B
4. DSP-1053 a novel serotonin reuptake inhibitor with 5-HT1A partial agonistic activity displays fast antidepressant effect with minimal undesirable effects in juvenile rats [O] . Taro Kato, Yuji Matsumoto, Masanori Yamamoto, 2015

机译：DSP-1053是一种具有5-HT1A部分激动活性的新型5-羟色胺再摄取抑制剂在幼年大鼠中显示出快速的抗抑郁作用而不良反应最小
5. Role of 5-HT1A autoreceptors in the mechanism of action of selective serotonin reuptake inhibitors: new findings from in vivo microdialysis studies [O] . Gardier A.M., Malagié I., Trillat A.C., 1996

机译：5-HT1A自身受体在选择性5-羟色胺再摄取抑制剂作用机制中的作用：体内微透析研究的新发现

SB-649915-B, a Novel 5-HT1A/B Autoreceptor Antagonist and Serotonin Reuptake Inhibitor, is Anxiolytic and Displays Fast Onset Activity in the Rat High Light Social Interaction Test

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