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Development of a human physiologically based pharmacokinetic (PBPK) model for phthalate (DEHP) and its metabolites: A bottom up modeling approach

机译：邻苯二甲酸盐（DEHP）及其代谢物的人生理基础药代动力学（PBPK）模型的发展：自下而期建模方法

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Raju Prasad Sharma; Marta Schuhmacher; Vikas Kumar;
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年度 2018
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1. Development of a human physiologically based pharmacokinetic (PBPK) model for phthalate (DEHP) and its metabolites: A bottom up modeling approach [J] . Raju Prasad Sharma, Marta Schuhmacher, Vikas Kumar Toxicology Letters: An International Journal Providing a Forum for Original and Pertinent Contributions in Toxicology Research . 2018,第期

机译：邻苯二甲酸酯（DEHP）及其代谢物的人生理学基础药代动力学（PBPK）模型的研制：自下而期建模方法
2. Characterizing uncertainty and population variability in the toxicokinetics of trichloroethylene and metabolites in mice, rats, and humans using an updated database, physiologically based pharmacokinetic (PBPK) model, and Bayesian approach. [J] . Chiu WA, Okino MS, Evans MV Toxicology and Applied Pharmacology . 2009,第1期

机译：使用更新的数据库，基于生理的药代动力学（PBPK）模型和贝叶斯方法表征小鼠，大鼠和人体内三氯乙烯和代谢物的毒物动力学的不确定性和种群变异性。
3. Development of a human physiologically based pharmacokinetic (PBPK) model for inorganic arsenic and its mono- and di-methylated metabolites. [J] . El Masri HA, Kenyon EM Journal of pharmacokinetics and pharmacodynamics . 2008,第1期

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4. A Physiologically Based Pharmacokinetic (PBPK) Model of nad-Paclitaxel Distribution in Mice and Humans [C] . Derek W. Bartlett, Willard R. Foss, Neil Desai Annual meeting exposition of the Controlled Release Society . 2010

机译：nad-紫杉醇在小鼠和人体中的基于生理的药代动力学（PBPK）模型
5. Mechanistic Physiologically Based Pharmacokinetic (PBPK) Modeling of Renal and Systemic Disposition of Drugs and Metabolites [D] . Huang, Weize. 2020

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6. Prediction of pharmacokinetics and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach: A case study of caffeine and ciprofloxacin [O] . Min-Ho Park, Seok-Ho Shin, Jin-Ju Byeon, 2017

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机译：同时生理基于生理学的药代动力学（PBPK）母体和活性代谢物的建模，研究复杂的CYP3A4药物 - 药物相互作用电位：中豚鼠的情况实例
8. Availability of Acute and/or Subacute Toxicokinetic Data for Select Compounds for the Rat and Physiologically Based Pharmacokinetic (PBPK) Models for Rats and Humans for Those Compounds. [R] . Sweeney, L. M., Goodwin, M. R. 2017

机译：用于大鼠的选择化合物的急性和/或亚急性毒代动力学数据的可用性和用于那些化合物的大鼠和人的基于生理学的药代动力学（pBpK）模型。

Development of a human physiologically based pharmacokinetic (PBPK) model for phthalate (DEHP) and its metabolites: A bottom up modeling approach

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