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Detection of Mutant Huntingtin Aggregation Conformers and Modulation of SDS-Soluble Fibrillar Oligomers by Small Molecules

机译：小分子检测突变亨廷丁蛋白聚集体和SDS溶性纤维寡聚体的调节

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Emily Mitchell Sontag; Gregor P. Lotz; Guocheng Yang; Christopher J. Sontag; Brian J. Cummings; Charles G. Glabe; Paul J. Muchowski; Leslie Michels Thompson;
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1. Tracking Mutant Huntingtin Aggregation Kinetics in Cells Reveals Three Major Populations That Include an Invariant Oligomer Pool [J] . Maya Olshina, Lauren Angley, Yasmin Ramdzan, The Journal of biological chemistry . 2010,第28期

机译：追踪突变体亨廷特林聚集动力学在细胞中显示出三种主要种群，包括不变的低聚物池
2. Small molecule-mediated co-assembly of amyloid-β oligomers reduces neurotoxicity through promoting non-fibrillar aggregation [J] . Hao Liu, Chengyuan Qian, Tao Yang, Chemical science . 2020,第27期

机译：淀粉样蛋白-β低聚物的小分子介导的共组装通过促进非纤维状聚集来减少神经毒性
3. Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction [J] . Goswami A, Dikshit P, Mishra A, Biochemical and Biophysical Research Communications . 2006,第1期

机译：氧化应激通过模拟蛋白酶体功能失常促进突变型亨廷顿蛋白聚集和突变型亨廷顿蛋白依赖性细胞死亡
4. Modulation cancellation method for detection of molecules with unresolved absorption bands [C] . Kosterev, Anatoliy A., Thomazy, David, Dong, Lei, CLEO;Conference on Lasers and Electro-Optics;Quantum Electronics and Laser Science Conference;QELS . 2010

机译：用于检测具有未解析吸收带的分子的调制消除方法
5. Mechanisms of modulation of N-methyl-D-aspartate (NMDA) receptors by mutant huntingtin. [D] . Fan, Mannie Man Yee. 2007

机译：突变亨廷顿蛋白调节N-甲基-D-天冬氨酸（NMDA）受体的机制。
6. Detection of Mutant Huntingtin Aggregation Conformers and Modulation of SDS-Soluble Fibrillar Oligomers by Small Molecules [O] . Emily Mitchell Sontag, Gregor P. Lotz, Guocheng Yang, -1

机译：小分子检测突变亨廷丁蛋白聚集体和SDS溶性纤维寡聚体的调节
7. Tracking Mutant Huntingtin Aggregation Kinetics in Cells Reveals Three Major Populations That Include an Invariant Oligomer Pool* [O] . Olshina, Maya A., Angley, Lauren M., Ramdzan, Yasmin M., 2010

机译：追踪细胞中突变的亨廷顿蛋白聚集动力学揭示了三个主要种群，其中包括不变的低聚物池*

Detection of Mutant Huntingtin Aggregation Conformers and Modulation of SDS-Soluble Fibrillar Oligomers by Small Molecules

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