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Genetic data from 15 STR loci for forensic individual identification and parentage analyses in UK domestic dogs (Canis lupus familiaris)

机译:来自英国国内犬的法医个体鉴定和父母级分析的15 str基因座的遗传数据(Canis Lupus熟悉)

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摘要

Eighteen STR loci and one sex determination locus present in the Finnzymes Canine 2.1 STR Multiplex Reagent Kit were screened in the UK dog population providing allele frequencies and population genetic parameters necessary for the application of STRs to forensic genetic casework. A total of 375 dogs were genotyped, including representative samples from each of twelve breeds used to evaluate Hardy–Weinberg equilibrium and calculate inter-population pairwise FST values. Three loci were excluded from calculations of average random match probability due to deviations from Hardy–Weinberg Equilibrium or ambiguous genotyping. Random match probability based on fifteen STR loci and one sex locus was subsequently estimated to be 2.8 × 10−17 for unrelated individuals across breeds.
机译:在英国犬群中筛选芬霉菌犬甘氨酸犬类犬类犬类犬类犬多重试剂试剂盒中存在的十八株洛杉矶。在英国狗群中提供等位基因频率和群体遗传参数,以应用strs以法医遗传案件。总共375只犬基因分型,包括来自12种生殖中每种的代表性样本用于评估Hardy-Weinberg平衡并计算群体群体对FST值。由于Hardy-Weinberg均衡或模糊基因分型的偏差,从平均随机匹配概率计算中排除了三个基因座。随后估计基于十五个STR基因座的随机匹配概率和一个性别轨迹的跨越品种的无关个体是2.8×10-17。

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