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Effect of three single-nucleotide polymorphisms in CAPN1 gene on beef tenderness (Brief Report)

机译:CAPN1基因的三个单核苷酸多态性对牛肉嫩度的影响(简要报告)

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摘要

Meat tenderness is an important trait in beef cattle production, as consumers considertenderness the most important attribute of beef palatability. There is ample evidencethat post mortem proteolysis of myofibrillar proteins is responsible for the decline in shearforce during storage. The bovine gene encodes the large subunit of μ-calpain, which is thought to be one of the mostimportant enzymes involved in tenderization (KOOHMARAIE 1996). Threesingle-nucleotide polymorphisms (SNPs) on the gene (316, 530 and 4 751 markers)have been associated with tenderness in different cattle breeds (PAGE et al. 2002, PAGE etal. 2004, WHITE et al. 2005). A more recent study confirmed that markers 316 and 4 751had an effect on beef tenderness (VAN EENENNAAM et al. 2007). The objective of thisresearch was to determine the existence of polymorphisms and to assess the effect of thereported SNP in the bovine gene on tenderness from a sample of Angus andBrangus steers fattened on pasture.
机译:肉的嫩度是肉牛生产中的重要特征,因为消费者认为嫩度是牛肉适口性的最重要属性。有足够的证据表明,肌原纤维蛋白的验尸蛋白水解是造成储存过程中剪切力下降的原因。牛基因编码μ-钙蛋白酶的大亚基,后者被认为是参与嫩化的最重要的酶之一(KOOHMARAIE 1996)。基因(316、530和4 751个标记)上的三单核苷酸多态性(SNP)与不同的牛品种的嫩度相关(PAGE等,2002; PAGE等,2004; WHITE等,2005)。最近的一项研究证实,标记316和4 751对牛肉嫩度有影响(VAN EENENNAAM等,2007)。这项研究的目的是确定多态性的存在,并评估牛基因中所报道的SNP对牧场上肥育的安格斯牛和黑背牛ste的嫩度的影响。

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