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Brassicasterol from Edible Aquacultural Hippocampus abdominalis Exerts an Anti-Cancer Effect by Dual-Targeting AKT and AR Signaling in Prostate Cancer

机译：来自食用水上水果的Brassicasterol Abdominalis通过双靶向AKT和前列腺癌信号传导施用抗癌作用

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Yinzhu Xu; Sooin Ryu; You-Kyung Lee; Hyo-Jeong Lee;
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1. Maclurin exerts anti-cancer effects on PC3 human prostate cancer cells via activation of p38 and inhibitions of JNK, FAK, AKT, and c-Myc signaling pathways [J] . Lee Yu Jin, Jung Okkeun, Lee Jongsung, Nutrition Research . 2018,第期

机译：Maclurin通过激活P38和JNK，FAK，AKT和C-MYC信号传导途径的激活施加对PC3人前列腺癌细胞的抗癌作用
2. Ginsenoside 20(S)-Rh2 exerts anti-cancer activity through the Akt/GSK3 signaling pathway in human cervical cancer cells [J] . Shi Xin, Yang Ji, Wei Gang Molecular medicine reports . 2018,第3aPta2期

机译：人参皂苷20（S）-RH2通过人宫颈癌细胞中的AKT / GSK3信号通路施加抗癌活性
3. Anti-cancer effects of torulene, isolated from Sporidiobolus pararoseus, on human prostate cancer LNCaP and PC-3 cells via a mitochondrial signal pathway and the down-regulation of AR expression [J] . Chao Du, Yahui Guo, Yuliang Cheng, RSC Advances . 2017,第5期

机译：分离自 Sporidiobolus pararoseus 的甲苯对人前列腺癌LNCaP和PC-3细胞通过线粒体信号通路的抗癌作用及AR表达的下调

4. S9, a Novel Anticancer Agent, Exerts Its Anti-Proliferative Activity by Interfering with Both PI3K-Akt-mT0R Signaling and Microtubule Cytoskeleton [C] . Chao Zhang, Hua-liang Jiang, Ling-hua Meng, ICMSI;International conference of molecular simulations and applied informatics technologies . 2010

机译：S9，一种新型的抗癌药，通过干扰PI3K-Akt-mT0R信号传导和微管细胞骨架来发挥其抗增殖活性

5. Multiple Akt/PKB-independent survival signaling pathways inhibit apoptosis in LNCaP prostate cancer cells. [D] . Carson, Jonathan Paul. 2002

机译：多个独立于Akt / PKB的生存信号通路抑制LNCaP前列腺癌细胞的凋亡。

6. Brassicasterol from Edible Aquacultural [O] . Yinzhu Xu, Sooin Ryu, You-Kyung Lee, 2020

机译：从食用水果中的晶圆化醇

7. Concurrent treatment with simvastatin and NF-κB inhibitor in human castration-resistant prostate cancer cells exerts synergistic anti-cancer effects via control of the NF-κB/LIN28/let-7 miRNA signaling pathway. [O] . Minyong Kang, Kyoung-Hwa Lee, Hye Sun Lee, 2017

机译：在人去势抵抗性前列腺癌细胞中同时用辛伐他汀和NF-κB抑制剂治疗通过控制NF-κB/ LIN28 / let-7 miRNa信号传导途径发挥协同抗癌作用。

8. Dual-Targeting of AR and Akt Pathways by Berberine in Castration-Resistant Prostate Cancer. [R] . Zhang, H. 2016

机译：抗小鼠前列腺癌中小檗碱对aR和akt通路的双靶向作用。

1. PI3K/AKT信号传导通路在血管瘤发生发展中的作用及靶向该通路治疗血管瘤的实验研究 [A] . 郑宁宁 . 2010

1. (54) Title: SUPPRESSION OF CANCER METASTASIS (57) Abstract: Methods are provided for suppressing cancer metastasis. Cancer metastasis is the most common cause of treatment failure and death in cancer patients. Tumor cell invasion and/or migration can be significantly inhibited after fibrillar proteins (rVPl, F-HSA, and F-BSA) treatment in vitro. In addition, rVPl can significantly suppress murine and human breast cancer metastasis and human prostate and ovarian cancer metastasis in vivo while F-HSA can significantly suppress murine breast cancer metastasis. Compositions of fibrillar proteins as anti-cancer metastasis therapeutics and methods of use thereof are provided herein. [P] . 外国专利： IN2012MN01463A . 2012-08-24

机译：（54）标题：抑制癌转移（57）摘要：提供了抑制癌转移的方法。癌症转移是癌症患者治疗失败和死亡的最常见原因。在体外处理原纤维蛋白（rVP1，F-HSA和F-BSA）后，肿瘤细胞的侵袭和/或迁移可以得到显着抑制。另外，rVP1可以在体内显着抑制鼠和人乳腺癌的转移以及人前列腺和卵巢癌的转移，而F-HSA可以显着地抑制鼠的乳腺癌的转移。本文提供了作为抗癌转移治疗剂的原纤维蛋白的组合物及其使用方法。

2. SUBSTITUTED 2-THIOXO-IMIDAZOLIDIN-4-ONES AND SPIRO ANALOGUES THEREOF, ACTIVE ANTI-CANCER INGREDIENT, PHARMACEUTICAL COM¬POSITION, MEDICINAL PREPARA¬TION, METHOD FOR TREATING PROSTATE CANCER [P] . 外国专利： GEP20207096B . 2020-04-10

机译：取代的2-噻吩并咪唑啉-4-酮及其螺类似物，活性抗癌成分，药物成分，药物制备，治疗前列腺癌的方法

3. Composition for enhancing sensibility for anti-cancer drug of prostate cancer and use of thereof [P] . 外国专利： KR20200045355A . 2020-05-04

机译：用于增强前列腺癌抗癌药敏感性的组合物及其用途

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Brassicasterol from Edible Aquacultural Hippocampus abdominalis Exerts an Anti-Cancer Effect by Dual-Targeting AKT and AR Signaling in Prostate Cancer

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