Technical Note: Synthesis of isoprene atmospheric oxidation products: isomeric epoxydiols and the rearrangement products cis- and trans-3-methyl-3,4-dihydroxytetrahydrofuran

摘要

Isoprene epoxydiol (IEPOX) isomers are key gas-phase intermediates ofisoprene atmospheric oxidation. Secondary organic aerosols derived from suchintermediates have important impacts on air quality and health. We reporthere convergent and unambiguous pathways developed for the synthesis ofisomeric IEPOX species and the rearrangement products - and -3-methyl-3,4-dihydroxytetrahydrofuran in good yield. The availability ofsuch compounds is necessary to expedite research on isoprene atmosphericoxidation mechanisms and subsequent aerosol formation as well as thetoxicological properties of the aerosols.